The role of distress intolerance for panic and nicotine withdrawal symptoms during a biological challenge

Journal of Psychopharmacology
Samantha G FarrisTeresa M Leyro

Abstract

Distress intolerance is linked to the maintenance of panic disorder and cigarette smoking, and may underlie both problems. Smokers (n = 54; 40.7% panic disorder) were recruited for an experimental study; half were randomly assigned to 12-hour nicotine deprivation and half smoked as usual. The current investigation consisted of secondary, exploratory analyses from this larger experimental study. Four distress intolerance indices were examined as predictors of anxious responding to an emotional elicitation task (10% carbon dioxide (CO2)-enriched air challenge); anxious responding was in turn examined as a predictor of post-challenge panic and nicotine withdrawal symptoms. The Distress Tolerance Scale (DTS) was significantly negatively associated with anxious responding to the challenge (β = -0.41, p = 0.017). The DTS was negatively associated with post-challenge increases nicotine withdrawal symptoms indirectly through the effect of anxious responding to the challenge (b = -0.485, CI95% (-1.095, -0.033)). This same indirect effect was found for post-challenge severity of panic symptoms (b = -0.515, CI95% (-0.888, -0.208)). The DTS was directly predictive of post-challenge increases nicotine withdrawal symptoms, in the opposite di...Continue Reading

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Citations

May 29, 2016·Addictive Behaviors·Samantha G FarrisJanice A Blalock
Aug 28, 2016·Behaviour Research and Therapy·Samantha G FarrisMichael J Zvolensky
Apr 22, 2016·Journal of Psychopharmacology·Samantha G Farris, Michael J Zvolensky
Aug 24, 2018·Nicotine & Tobacco Research : Official Journal of the Society for Research on Nicotine and Tobacco·Samantha G FarrisMichael J Zvolensky
Nov 2, 2018·International Journal of Behavioral Medicine·Samantha G FarrisAngelo M DiBello
Mar 4, 2020·International Journal of Behavioral Medicine·Emily K BurrSamantha G Farris
Mar 9, 2019·Journal of General Internal Medicine·Robert M AnthenelliA Eden Evins

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