PMID: 6408668Jan 1, 1983Paper

The role of dopaminergic receptors in the behavioral effects induced by lisuride in male rats

Psychopharmacology
G Baggio, F Ferrari

Abstract

Lisuride increased the incidence of stretching and yawning (SY) as well as of penile erection (PE) and elicited stereotyped behavior (SB), aggressive behavior and mounting in male rats, depending on the dose used. SY was prevented by two dopaminergic antagonists, haloperidol and sulpiride, but not by methysergide, a serotoninergic antagonist, while PE was antagonized by all three drugs. With regard to SB, aggressive behavior and mounting, all three were suppressed by haloperidol; sulpiride, while partially antagonizing aggressiveness, failed to affect SB and mounting; methysergide did not significantly influence any of the three. This suggests that lisuride principally affects the dopaminergic system. Although further detailed studies are required to elucidate which type of the complex population of DA-receptors is involved in each kind of behavior, we suggest that SY at least is due to the activation by lisuride of presynaptic DA-receptors.

References

Nov 1, 1978·European Journal of Pharmacology·M K MenonJ L Neumeyer
Apr 1, 1976·European Journal of Pharmacology·R Horowski, H Wachtel
May 1, 1973·The Journal of Pharmacy and Pharmacology·H CorrodiU Ungerstedt
Jun 1, 1974·The Journal of Pharmacy and Pharmacology·G N WoodruffA R Crossman
Sep 1, 1972·The Journal of Pharmacy and Pharmacology·W KehrC Atack
May 30, 1980·European Journal of Pharmacology·S AhleniusL Svensson
Dec 1, 1977·Neuroscience Letters·M Da PradaH H Keller

❮ Previous
Next ❯

Citations

Jan 1, 1986·Psychopharmacology·F FerrariG Baggio
Jan 1, 1989·Psychopharmacology·F FerrariV Mangiafico
Dec 1, 1995·Psychopharmacology·M R ZarrindastM Mohagheghi-Badi
Aug 3, 1984·European Journal of Pharmacology·A J GowerC L Broekkamp
Jul 13, 1984·European Journal of Pharmacology·F Gonzalez-LimaR Medina
Mar 18, 1986·European Journal of Pharmacology·A J GowerC L Broekkamp
Jan 21, 1986·European Journal of Pharmacology·G SerraG L Gessa
Nov 30, 1993·European Journal of Pharmacology·F Ferrari, D Giuliani
Jun 15, 1987·Life Sciences·F FerrariV Mangiafico
Feb 1, 1990·Physiology & Behavior·A BenelliA Bertolini
Oct 1, 1993·Physiology & Behavior·F Ferrari, D Giuliani
Nov 1, 1994·Physiology & Behavior·F Ferrari, D Giuliani
Aug 1, 1984·Pharmacology, Biochemistry, and Behavior·M D Schechter
Apr 1, 1985·Pharmacology, Biochemistry, and Behavior·S D Mendelson, B B Gorzalka
Feb 1, 1987·Pharmacology, Biochemistry, and Behavior·G SerraG L Gessa
Sep 1, 1991·Pharmacology, Biochemistry, and Behavior·S Chiavegatto, M M Bernardi
Apr 1, 1992·Pharmacology, Biochemistry, and Behavior·F FerrariD Giuliani
Jan 1, 1995·Pharmacology, Biochemistry, and Behavior·F Ferrari, D Giuliani
Mar 1, 1996·Pharmacology, Biochemistry, and Behavior·F Ferrari, D Giuliani
Jan 1, 1995·Neuroscience and Biobehavioral Reviews·M R Melis, A Argiolas
Jan 1, 1987·Behavioural Brain Research·R Bell, P G Hepper
Mar 1, 1988·Brain Research Bulletin·D BitranK J Lookingland
Nov 20, 1990·The Journal of Steroid Biochemistry and Molecular Biology·G FrajeseD Nerozzi
Apr 29, 1998·European Journal of Pharmacology·A Argiolas, M R Melis
Jul 6, 2000·Neuroscience and Biobehavioral Reviews·F Giuliano, O Rampin
Mar 1, 1992·British Journal of Pharmacology·M R Zarrindast, A Jamshidzadeh
Oct 23, 1998·Pharmacology & Toxicology·M Ghazi-KhansariM R Zarrindast
Jan 1, 1990·Annals of the New York Academy of Sciences·B B GorzalkaN V Watson
Sep 28, 2005·Expert Opinion on Therapeutic Targets·Yasin TemelVeerle Visser-Vandewalle
Jun 1, 1985·Pharmacological Research Communications·F Ferrari
Jan 1, 1987·Neuroscience and Biobehavioral Reviews·D Bitran, E M Hull
Oct 1, 1992·Pharmacological Research : the Official Journal of the Italian Pharmacological Society·F FerrariD Giuliani

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.