PMID: 8117468Jan 1, 1994

The role of encapsulated anaerobic bacteria in synergistic infections

FEMS Microbiology Reviews
I Brook


The effect of encapsulation on the virulence, survival, and protection of anaerobic bacteria from phagocytosis is reviewed. Support for the importance of encapsulated Gram-negative anaerobic rods (Bacteroides sp., Prevotella sp. and Porphyromonas sp.), anaerobic and facultative Gram-positive cocci (AFGPC) was provided by their higher recovery rate in oropharyngeal infections, abscesses and blood, compared to their number in the normal flora. The pathogenicity of Bacteroides, Fusobacterium, Clostridium, and AFGPC was studied by inoculating them into mice and observing their ability to induce subcutaneous abscesses. Encapsulated Bacteroides, Fusobacteria, and AFGPC generally induced abscesses, whereas non-encapsulated organisms did not. However, many of the strains that had only a minimal number of encapsulated organisms (< 1%) survived in the abscesses, and they became heavily encapsulated when inoculated with other viable or non-viable encapsulated bacteria. Thereafter, these strains were able to induce abscesses when injected alone. Encapsulated Gram-negative anaerobic rods and AFGPC-induced bacteraemia and translocation, and increased the mortality of the infected animals more often than did the non-encapsulated form of the s...Continue Reading


Dec 17, 1977·Lancet·H R InghamA A Codd
Mar 1, 1977·The Journal of Infectious Diseases·S M Finegold
Feb 1, 1978·Applied and Environmental Microbiology·S BurtD T Jones
Mar 1, 1978·Infection and Immunity·A B OnderdonkJ G Bartlett
Nov 1, 1992·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·T Hofstad
Nov 1, 1986·The Journal of Infection·I Brook, R I Walker
Mar 1, 1986·Journal of Medical Microbiology·I Brook, R I Walker
Sep 1, 1986·Journal of Medical Microbiology·I Brook
Apr 1, 1986·Journal of General Microbiology·S PatrickA Coffey
Feb 1, 1987·Journal of Medical Microbiology·I Brook
Feb 1, 1985·Canadian Journal of Microbiology·I Brook, R I Walker
Oct 1, 1971·Journal of Bacteriology·M LevA F Milford
Jan 1, 1981·Critical Reviews in Microbiology·J W CostertonK J Cheng
Aug 1, 1982·Journal of Medical Microbiology·G R Jones, C G Gemmell
Jun 1, 1984·European Journal of Clinical Microbiology·I BrookR I Walker
Oct 1, 1984·Journal of Medical Microbiology·F NamavarD M MacLaren
Dec 1, 1983·Infection and Immunity·I Brook, R I Walker
Jun 1, 1984·Journal of Medical Microbiology·S PatrickM J Larkin
Aug 1, 1984·Infection and Immunity·I Brook, R I Walker
Jan 1, 1982·The Journal of Clinical Investigation·A B OnderdonkD L Kasper
Jan 1, 1980·Infection and Immunity·D Mayrand, B C McBride
Nov 1, 1980·American Journal of Diseases of Children·I BrookW J Martin
Jan 1, 1994·Chemotherapy·I Brook, J D Gillmore
Jul 1, 1993·Journal of Clinical Microbiology·A PantostiD L Kasper
Jul 1, 1958·The Journal of Infectious Diseases·S E MERGENHAGENH W SCHERP
Jan 1, 1949·The Journal of Infectious Diseases·K E HITEH C HESSELTINE
Jul 1, 1949·The Journal of Experimental Medicine·W B WOOD, M R SMITH


Feb 12, 2008·American Journal of Respiratory and Critical Care Medicine·Michael M TunneyJ Stuart Elborn
Nov 1, 1995·Journal of Vascular and Interventional Radiology : JVIR·E S MaldenW C Dunagan
Dec 13, 2012·Archives of Plastic Surgery·Sang Gue GangMin Sung Tark
Mar 20, 2015·Clinical Microbiology Reviews·Eija Könönen, William G Wade
Feb 1, 2002·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·Christos GeorgalasKalpesh S Patel

Related Concepts

Bacteria, Anaerobic
Bacterial Infections
Bacterial Capsules

Trending Feeds


Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Neural Activity: Imaging

Imaging of neural activity in vivo has developed rapidly recently with the advancement of fluorescence microscopy, including new applications using miniaturized microscopes (miniscopes). This feed follows the progress in this growing field.

The Tendon Seed Network

Tendons are rich in the extracellular matrix and are abundant throughout the body providing essential roles including structure and mobility. The transcriptome of tendons is being compiled to understand the micro-anatomical functioning of tendons. Discover the latest research pertaining to the Tendon Seed Network here.

Myocardial Stunning

Myocardial stunning is a mechanical dysfunction that persists after reperfusion of previously ischemic tissue in the absence of irreversible damage including myocardial necrosis. Here is the latest research.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.


Incretins are metabolic hormones that stimulate a decrease in glucose levels in the blood and they have been implicated in glycemic regulation in the remission phase of type 1 diabetes. Here is the latest research.

Chromatin Regulation and Circadian Clocks

The circadian clock plays an important role in regulating transcriptional dynamics through changes in chromatin folding and remodelling. Discover the latest research on Chromatin Regulation and Circadian Clocks here.

Long COVID-19

“Long Covid-19” describes illness in patients who are reporting long-lasting effects of the SARS-CoV-19 infection, often long after they have recovered from acute Covid-19. Ongoing health issues often reported include low exercise tolerance and breathing difficulties, chronic tiredness, and mental health problems such as post-traumatic stress disorder and depression. This feed follows the latest research into Long Covid.

Spatio-Temporal Regulation of DNA Repair

DNA repair is a complex process regulated by several different classes of enzymes, including ligases, endonucleases, and polymerases. This feed focuses on the spatial and temporal regulation that accompanies DNA damage signaling and repair enzymes and processes.

Related Papers

International Journal of Infectious Diseases : IJID : Official Publication of the International Society for Infectious Diseases
I Brook, E H Frazier
Journal of Huazhong University of Science and Technology. Medical Sciences = Hua Zhong Ke Ji Da Xue Xue Bao. Yi Xue Ying De Wen Ban = Huazhong Keji Daxue Xuebao. Yixue Yingdewen Ban
Changzheng HuangDemei Zhang
© 2021 Meta ULC. All rights reserved