The role of endoscopic treatment of vesicoureteral reflux: a 17-year experience

The Journal of Urology
Nicola CapozzaPaolo Caione

Abstract

During the last 20 years endoscopic treatment of vesicoureteral reflux (VUR) has gained popularity in European countries. We performed a retrospective analysis of our 17-year experience with more than 1,000 patients treated to assess whether technique, indications or results of endoscopic treatment of VUR have changed over time. From January 1986 to June 2002, 1,244 patients underwent endoscopic treatment for grades II to IV VUR. Polytetrafluoroethylene was injected as the bulking material in the first 14 cases, after 1989 bovine cross-linked collagen was used in 442 and since 1995 dextranomer/hyaluronic acid copolymer was used in 788. Urinary tract ultrasound was performed 1 and 6 months, and micturition cystourethrogram was done 3 and 12 months after endoscopic treatment. All patients included in the study completed a minimum 12-month followup. Endoscopic treatment was always performed in 1 day. Complications were observed in 0.5% of cases. After 1 or 2 injections the micturition cystourethrogram showed no significant VUR (absent or grade I) in 77% of cases. The success rate was 88%, 75% and 52% for grades II, III and IV VUR, respectively. With increasing experience not only primary VUR, but also secondary reflux was consider...Continue Reading

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Citations

Feb 6, 2007·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Nicola Capozza, Paolo Caione
Jun 30, 2011·International Urology and Nephrology·Aydin H PooliAbdol-Mohammad Kajbafzadeh
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Oct 20, 2007·Current Medical Research and Opinion·Terry W HensleMichael Eaddy
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Mar 26, 2011·Journal of Pediatric Urology·S LujánF García-Ibarra
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