Abstract
Members of the epidermal growth factor receptor family (ErbB family) possess a wide distribution and diverse functions ranging from cellular growth to migration and apoptosis. Though highly implicated in a variety of cancers, their involvement in infectious disease is less recognised. A growing body of evidence now highlights the importance of the ErbB family in a variety of infections. Their role as growth factor receptors, along with other characteristics, such as surface expression and continuous intracellular trafficking, make this receptor family ideally placed for exploitation by pathogens. Herein, we review our current understanding of the role of the ErbB family in the context of infectious disease, exploring the mechanisms that govern pathogen exploitation of this system.
Citations
Mar 18, 2020·Cells·Jemima HoJulian R Naglik
May 28, 2019·Nature Communications·Jemima HoJulian R Naglik
Aug 31, 2020·Oral Diseases·Velia Ramírez-AmadorWipawee Nittayananta
Sep 11, 2020·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·Mengling YouDan Ji
Aug 16, 2018·MBio·Tonya N WatkinsVincent M Bruno
Jan 27, 2019·Scientific Reports·Yalitza Lopez CorcinoCarlos S Subauste
Sep 19, 2019·Science Signaling·Gholamreza Haqshenas, Christian Doerig
Jun 18, 2020·Frontiers in Microbiology·Werner J D OuwendijkGeorges M G M Verjans
Sep 6, 2020·Microorganisms·Anna Pavlova, Irshad Sharafutdinov
Aug 10, 2019·Frontiers in Cellular and Infection Microbiology·Paul J HansonDecheng Yang
Jul 10, 2019·Current Opinion in Microbiology·Julian R NaglikBernhard Hube
Nov 18, 2020·International Journal of Molecular Sciences·Jorge Esteban-VillarrubiaJavier Molina-Cerrillo
Feb 12, 2021·Brain, Behavior, and Immunity·Ibrahim A AkkouhAttila Szabo
Oct 29, 2020·Epigenetics & Chromatin·Regan J HaywardGarry S A Myers
Jun 1, 2021·Frontiers in Pharmacology·Jazlyn P BorgesBenjamin E Steinberg
Jul 26, 2021·Cellular Signalling·Srikanth PalanisamyKathleen Gabrielson
May 26, 2021·Infection and Immunity·Sara ScuteraTiziana Musso
Jul 12, 2021·Biomedicine & Pharmacotherapy = Biomédecine & Pharmacothérapie·Yumi HaradaNaoki Fujitsuka
Aug 8, 2021·Microorganisms·Ilena BenoitRenée N Douville
Aug 20, 2021·Frontiers in Immunology·Qinzhi YangMao Luo
Oct 3, 2018·Journal of Proteome Research·Jun SunRong Liu
Sep 14, 2021·PeerJ·João Luiz de Lemos Padilha PittaAntonio Mauro Rezende
Dec 7, 2021·Frontiers in Medicine·Kotakonda ArunasriSisinthy Shivaji