PMID: 19948697Dec 2, 2009Paper

The role of fibrin sealants in orthopaedic surgery

The Journal of the American Academy of Orthopaedic Surgeons
R Justin Thoms, Scott E Marwin

Abstract

Blood conservation, specifically the avoidance of allogeneic blood transfusion, is becoming an important aspect of preoperative planning and intraoperative decision making in orthopaedic surgery. Knee and hip arthroplasty, as well as certain spine procedures, place patients at risk of significant blood loss. Fibrin sealants are topically applied hemostatic agents that reduce the time required to achieve hemostasis as well as the volume of blood loss. Fibrin sealants may provide additional benefits beyond hemostasis, such as improvements in wound healing and postoperative range of motion as well as lower rates of wound infections.

Associated Clinical Trials

References

Aug 1, 1996·The Journal of Bone and Joint Surgery. American Volume·M J Lemos, W L Healy
Jan 1, 1997·The Annals of Thoracic Surgery·A M ScheuleG Ziemer
Feb 11, 1999·The Journal of Bone and Joint Surgery. American Volume·B E BierbaumR B Welch
May 9, 2000·The Annals of Thoracic Surgery·W BeierleinG Ziemer
Mar 22, 2002·The Journal of Pharmacology and Experimental Therapeutics·Roman FurtmüllerHeinz Redl
May 9, 2002·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·Michael VaimanSamuel Segal
Dec 10, 2002·The Journal of the American Academy of Orthopaedic Surgeons·E Michael Keating, John B Meding
Sep 16, 2003·Spine·Bradley K Weiner, Matthew Walker
Oct 3, 2003·Medicine and Science in Sports and Exercise·Mikel SánchezIñigo Mujika
Dec 3, 2003·Journal of Long-term Effects of Medical Implants·Gwo-Jaw WangUNKNOWN Orthopaedic Investigators Group
Feb 12, 2004·Seminars in Hematology·Joseph D Tobias
Jun 16, 2004·Critical Care : the Official Journal of the Critical Care Forum·Lawrence T Goodnough
Oct 29, 2004·Plastic and Reconstructive Surgery·Barry L EppleyJoel Higgins
Jan 26, 2005·Current Opinion in Hematology·Katherine I Schexneider
Feb 1, 2005·The Annals of Thoracic Surgery·Wolfram BeierleinGerhard Ziemer
Dec 6, 2005·The Journal of Craniofacial Surgery·William S Pietrzak, Barry L Eppley
Mar 31, 2006·Journal of the American College of Surgeons·David M Albala, Jeffrey H Lawson
Apr 29, 2006·Acta Anaesthesiologica Scandinavica·P A M EvertsA van Zundert
Jun 1, 2006·The American Journal of Sports Medicine·Allan Mishra, Terri Pavelko
Jul 27, 2006·Orthopedics·William J BerghoffRichard D Rhodes
Aug 12, 2006·The Annals of Otology, Rhinology, and Laryngology·Michael VaimanHaim Gavriel
Sep 9, 2006·Clinical and Applied Thrombosis/hemostasis : Official Journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis·Michael Rud LassenHelle Coff Ganes
Sep 29, 2006·Orthopedics·Viktor E KrebsRobert Helfand
Nov 14, 2006·The American Journal of Sports Medicine·Mikel SánchezIñigo Mujika
Nov 16, 2006·European Journal of Anaesthesiology·D RoystonP De Vooght
Feb 27, 2007·Knee Surgery, Sports Traumatology, Arthroscopy : Official Journal of the ESSKA·Peter A M EvertsAndré van Zundert
Mar 11, 2008·The American Journal of Sports Medicine·Marieke de MosGerjo J V M van Osch
May 2, 2008·Journal of Orthopaedic Trauma·Massimo MaricondaCarlo Milano
Jul 16, 2008·Current Opinion in Otolaryngology & Head and Neck Surgery·John YooRoxanne Cosby
Dec 24, 2008·Journal of Orthopaedic Trauma·Mikel SanchezIsabel Andia

❮ Previous
Next ❯

Citations

Mar 4, 2014·Orthopedics·Neil V Shah, Robert Meislin
Dec 12, 2012·Orthopedics·John MansourPaul Lafferty
Sep 16, 2010·Orthopedics·Adolph V LombardiJoanne B Adams
Nov 28, 2013·Archives of Orthopaedic and Trauma Surgery·M C Struijk-MulderH B Ettema
Jun 12, 2021·Clinical and Applied Thrombosis/hemostasis : Official Journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis·Jong-Keun KimHyuk-Soo Han
Jun 3, 2014·Journal of Orthopaedic Surgery and Research·Hongsheng WangZhengdong Cai

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.