The role of flow limitation as an important diagnostic tool and clinical finding in mild sleep-disordered breathing

Sleep Science
Nevin AroraC Guilleminault

Abstract

Obstructive sleep apnea (OSA) is defined by quantifying apneas and hypopneas along with symptoms suggesting sleep disruption. Subtler forms of sleep-disordered breathing can be missed when this criteria is used. Newer technologies allow for non-invasive detection of flow limitation, however consensus classification is needed. Subjects with flow limitation demonstrate electroencephalogram changes and clinical symptoms indicating sleep fragmentation. Flow limitation may be increased in special populations and treatment with nasal continuous positive airway pressure (CPAP) has been shown to improve outcomes. Titrating CPAP to eliminate flow limitation may be associated with improved clinical outcomes compared to treating apneas and hypopneas.

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Citations

Sep 9, 2016·European Clinical Respiratory Journal·Ulla AnttalainenTarja Saaresranta
Oct 13, 2016·ERJ Open Research·Christian GuilleminaultLauren Lo
Jun 22, 2017·Computational and Mathematical Methods in Medicine·Sheng-Cheng HuangKang-Ping Lin
Jul 10, 2021·Sleep·Dwayne L MannPhilip I Terrill
Dec 6, 2021·American Journal of Obstetrics and Gynecology·Kim PhanStella S Daskalopoulou

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