The role of functional magnetic resonance imaging in the study of brain development, injury, and recovery in the newborn

Seminars in Perinatology
Mohamed L Seghier, P S Huppi

Abstract

Development of brain functions and the structural-functional correlates of brain injury remain difficult to evaluate in the young infant. Thus, new noninvasive methods capable of early functional diagnosis are needed. This review describes the use of functional magnetic resonance imaging (fMRI) for studying localization of brain function in the developing brain when standard clinical investigations are not available or conclusive. This promising neuroimaging technique has been successfully used in healthy newborns and in newborns with brain injury using different paradigms, including passive visual, somato-sensorial, and auditory stimulation. We summarize the major findings of previous fMRI studies in young infants, describe ongoing methodological challenges, and propose exciting future developments in using resting-state protocols and functional connectivity techniques to assist in evaluating early life brain function and its recovery from injury.

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References

Jan 14, 1998·Neuroreport·H YamadaY Ishii
Mar 14, 1998·Proceedings of the National Academy of Sciences of the United States of America·B R RosenA M Dale
Jul 1, 1998·Annual Review of Biophysics and Biomolecular Structure·S OgawaK Ugurbil
Aug 14, 1999·Pediatric Research·E MartinV L Marcar
Aug 31, 1999·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·O Josephs, R N Henson
Jul 27, 2000·Human Brain Mapping·E MartinV L Marcar
Sep 12, 2000·Mental Retardation and Developmental Disabilities Research Reviews·S Y Bookheimer
Feb 16, 2002·Topics in Magnetic Resonance Imaging : TMRI·Russell A PoldrackP Ellen Grant
Mar 22, 2002·NeuroImage·Christopher R GenoveseThomas Nichols
Dec 10, 2002·Science·Ghislaine Dehaene-LambertzLucie Hertz-Pannier
Feb 21, 2003·Journal of Child Neurology·Anna Weber ByarsElena Plante
Sep 2, 2003·NeuroImage·K J FristonW Penny
Nov 5, 2003·Neuropediatrics·M WilkeW S Ball
Apr 3, 2004·Pediatrics·Heidelise AlsEric C Eichenwald
Jul 13, 2004·Pediatric Neurology·Byron Bernal, Nolan Altman
Jul 31, 2004·Radiology·Frank G Shellock, John V Crues
Aug 7, 2004·Stroke; a Journal of Cerebral Circulation·Bruno FernandezMichèle Allard
Oct 13, 2004·Neurology·Ferdinand Binkofski, Rüdiger J Seitz
Feb 15, 2005·Magnetic Resonance Imaging·Nikos K Logothetis, Josef Pfeuffer
Mar 1, 2005·NeuroImage·Alard RoebroeckRainer Goebel
May 3, 2005·Obstetrics and Gynecology·Cande V AnanthAnthony M Vintzileos
Aug 23, 2005·NeuroImage·Stephan G ErberichFloyd Gilles
Apr 6, 2006·Pediatrics·Suzanne MunsonMonique Ernst
May 2, 2006·Journal of Magnetic Resonance Imaging : JMRI·Eleni KotsoniB J Casey
Jun 30, 2006·International Journal of Psychophysiology : Official Journal of the International Organization of Psychophysiology·Michael B Miller, John Darrell Van Horn
Aug 23, 2006·Nature Reviews. Neuroscience·Paul M MatthewsEdward T Bullmore
Sep 2, 2006·Proceedings of the National Academy of Sciences of the United States of America·J S DamoiseauxC F Beckmann
Sep 12, 2006·Seminars in Fetal & Neonatal Medicine·Petra S Hüppi, Jessica Dubois
Sep 27, 2006·Seminars in Fetal & Neonatal Medicine·Mohamed L SeghierPetra S Huppi
Feb 9, 2007·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Sreepadma P SontyDarren R Gitelman
Mar 3, 2007·The American Journal of Psychiatry·Abigail G GarrityVince D Calhoun
May 5, 2007·NeuroImage·Mohamed L SeghierCathy J Price
Jul 4, 2007·Topics in Magnetic Resonance Imaging : TMRI·Ashok Panigrahy, Stefan Blüml

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Citations

Jun 28, 2012·Pediatric Radiology·Jean A TkachCharles L Dumoulin
Mar 12, 2013·Annals of Biomedical Engineering·A G AllieviE Burdet
Feb 15, 2014·Clinics in Perinatology·Soo Hyun KwonPetra S Huppi
Jul 5, 2011·Pediatric Neurology·Els L OrtibusLieven G Lagae
Oct 23, 2015·Cerebral Cortex·Alessandro G AllieviEtienne Burdet
Jun 22, 2012·Developmental Medicine and Child Neurology·Wayne LeeMargot J Taylor
Oct 29, 2010·Journal of Anatomy·Gregory A LodygenskyPetra S Hüppi
Aug 14, 2013·Developmental Medicine and Child Neurology·Susan M ReidDinah S Reddihough
Jan 24, 2014·Cerebral Cortex·Dustin ScheinostLaura R Ment
Sep 17, 2011·Neuroscience and Biobehavioral Reviews·Giovanni Mento, Patrizia Silvia Bisiacchi
Sep 5, 2012·The Journal of Pediatrics·Ruba BeniniUNKNOWN Registre de la Paralysie Cérébrale au Québec (Quebec Cerebral Palsy Registry) Consortium
Mar 31, 2015·Seminars in Perinatology·Christopher D Smyser, Jeffrey J Neil
Mar 7, 2015·Seminars in Perinatology·Shannon TocchioAshok Panigrahy
Oct 18, 2014·Frontiers in Neurology·Alessandro G AllieviEtienne Burdet
May 24, 2017·Annual Review of Vision Science·Stelios M Smirnakis
Mar 20, 2021·Brain Structure & Function·Patrizia Bisiacchi, Elisa Cainelli

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