PMID: 8606320Feb 1, 1996Paper

The role of functional status in predicting inpatient mortality with AIDS: a comparison with current predictors

Journal of Clinical Epidemiology
A C JusticeB J Turner

Abstract

To assess the independent prognostic role of functional status, as reflected by a measure of an inpatient's global requirement for nursing assistance with basic activities of daily living (Global ADL), we compared Global ADL with three validated AIDS mortality predictors: the Clinical AIDS Prognostic Staging (CAPS); the Severity Classification System for AIDS Hospitalization--version 2 (SCAH-2); and CD4 cell count. Our study sample consisted of 1392 patients with AIDS and a hospital stay of 3 or more days at one of 20 hospitals in 11 U.S. cities with high AIDS incidence. Data were collected from September 1990 through December 1991. Two percent of patients refused participation, and 26% were eliminated due to incomplete data collection, leaving an analytic sample of 1003 patients. Only 30% of patients had a CD4 count measured at any time during hospitalization. Cox regression was used to measure the hazard of inpatient mortality adjusted for length of stay. Overall mortality was 12%. Mortality rates for patients in Global ADL stages I-IV were 3%, 8%, 19%, and 51%, respectively (p < 0.0001). Global ADL more effectively discriminated mortality than CAPS (p < 0.001), SCAH-2 (p < 0.001), or CD4 count (p < 0.001). Global ADL also ad...Continue Reading

References

Jan 1, 1992·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·E VergerC Conill
Apr 1, 1992·American Journal of Public Health·L E MarksonT R Fanning
Jan 1, 1991·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·J WilliamsG Giles
Jul 25, 1990·JAMA : the Journal of the American Medical Association·R E ParkM R Chassin
Jan 19, 1990·JAMA : the Journal of the American Medical Association·R E Chaisson
Apr 15, 1990·Cancer·C ConillM Salamero
Apr 1, 1989·Medical Care·B J TurnerJ K Ball
May 25, 1989·The New England Journal of Medicine·A C JusticeC K Wells
Jan 9, 1986·The New England Journal of Medicine·R R RedfieldE C Tramont
May 23, 1986·MMWR. Morbidity and Mortality Weekly Report·UNKNOWN Centers for Disease Control (CDC)
Jan 1, 1985·Medical Decision Making : an International Journal of the Society for Medical Decision Making·R M Centor
Jan 1, 1970·The Gerontologist·S KatzR C Grotz
May 15, 1993·Annals of Internal Medicine·W A KnausE A Draper
May 20, 2009·BMC Gastroenterology·Peter JepsenHenrik Toft Sørensen

❮ Previous
Next ❯

Citations

Jun 17, 2009·Archives of Surgery·Margaret G StinemanBarbara E Bates
Jun 24, 2006·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Jeff A SloanUNKNOWN Clinical Significance Consensus Meeting Group
Sep 25, 2003·Journal of Clinical Epidemiology·Denise L JacobsonUNKNOWN Outcomes Committee of the Adult AIDS Clinical Trials Group
Apr 1, 1997·Journal of Clinical Epidemiology·J Fawcett, L Tulman
Dec 11, 1997·Journal of Clinical Epidemiology·L RabeneckN P Wray
Apr 16, 2002·Haemophilia : the Official Journal of the World Federation of Hemophilia·D R GlobeG Kominski
Dec 7, 2006·AIDS Research and Human Retroviruses·K K OurslerL I Katzel
Jan 22, 2004·Medical Care·Doris C VaheyDelfino Vargas
Jul 4, 2012·Cancer Nursing·Jingjing ShangLinda H Aiken
Apr 1, 1997·American Journal of Public Health·W el-Sadr, J D Neaton
Apr 1, 1997·American Journal of Public Health·G R SeageA M Epstein
Jan 1, 1997·American Journal of Public Health·L H AikenJ L Klocinski
Apr 1, 1997·Journal of General Internal Medicine·K E CovinskyC S Landefeld
May 15, 2002·Mayo Clinic Proceedings·Marlene H FrostUNKNOWN Clinical Significance Consensus Meeting Group
Apr 21, 2010·Health Services Research·Linda H AikenHerbert L Smith
Sep 3, 2011·Journal of Nursing Scholarship : an Official Publication of Sigma Theta Tau International Honor Society of Nursing·J Margo Brooks-CarthonLinda H Aiken
Jul 24, 2004·Journal of the American Geriatrics Society·Jean S KutnerConnie Beehler
Feb 15, 2015·American Journal of Infection Control·Jingjing ShangPatricia Stone
Jul 2, 2005·Oncology Nursing Forum·Christopher R Friese
Jul 1, 1997·Memórias do Instituto Oswaldo Cruz·M C Portela, K N Simpson
Jun 24, 2017·International Journal of Nursing Studies·Pauline A SwigerLori A Loan
Jun 28, 2000·AIDS Patient Care and STDs·P M Nemechek
Sep 24, 2004·Nursing Research·Patricia A Patrician
Oct 7, 2000·Stroke; a Journal of Cerebral Circulation·G R Williams, J G Jiang
Nov 11, 2005·Journal of Acquired Immune Deficiency Syndromes : JAIDS·Jennifer M ShenPeter A Selwyn
Aug 17, 1999·Medical Care·L H AikenA L Weber
Apr 12, 2013·Journal of Acquired Immune Deficiency Syndromes : JAIDS·Vagner RasoJúlia M DʼAndréa Greve
Feb 14, 2019·PM & R : the Journal of Injury, Function, and Rehabilitation·Conan SoJeffrey C Schneider

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.