The role of heliox in paediatric respiratory disease

Paediatric Respiratory Reviews
Marie D Frazier, Ira M Cheifetz

Abstract

Helium-oxygen (heliox) gas mixtures have been studied for over 70 years as an adjunctive therapy for airway obstruction in a variety of respiratory diseases. The medical use of heliox is based on the physical properties of helium as its low density makes it advantageous in promoting more efficient flow through narrowed passages. Clinical evidence of the efficacy of heliox in treating paediatric respiratory diseases is increasing in the medical literature. This article consists of a comprehensive review of the literature investigating the utility of heliox in the treatment of paediatric respiratory disorders, including upper and lower airway obstruction, mechanical ventilation, and aerosol delivery.

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Citations

Jan 5, 2014·Journal of Aerosol Medicine and Pulmonary Drug Delivery·I KatzG Caillibotte
Aug 13, 2015·Intensive Care Medicine Experimental·Charlotte J BeurskensNicole P Juffermans
Dec 31, 2014·Critical Care Research and Practice·Charlotte J BeurskensNicole P Juffermans
Feb 27, 2013·Annals of Thoracic Medicine·Sema YilmazSait Polat
Aug 7, 2013·Medical Gas Research·Carlos J Berganza, John H Zhang
Oct 22, 2013·International Journal of Pediatric Otorhinolaryngology·Marcela FandiñoAndrew Campbell
Apr 5, 2014·Computer Methods in Biomechanics and Biomedical Engineering·Laure GouinaudGeorges Caillibotte
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Oct 12, 2013·The Cochrane Database of Systematic Reviews·Candice BjornsonDavid W Johnson
Nov 15, 2018·Einstein·Milena Siciliano NascimentoCristiane do Prado
Oct 30, 2018·The Cochrane Database of Systematic Reviews·Irene MoraaMieke L van Driel
Jun 23, 2021·Journal of Intensive Care Medicine·Alicia LewAnthony A Sochet
Aug 17, 2021·The Cochrane Database of Systematic Reviews·Irene MoraaMieke L van Driel

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