The role of hippocampal adult neurogenesis in methamphetamine addiction

Brain Plasticity
Yoshio Takashima, Chitra D Mandyam

Abstract

One of the consequences of chronic methamphetamine (Meth) abuse and Meth addiction is impaired hippocampal function which plays a critical role in enhanced propensity for relapse. This impairment is predicted by alterations in hippocampal neurogenesis, structural- and functional-plasticity of granule cell neurons (GCNs), and expression of plasticity-related proteins in the dentate gyrus. This review will elaborate on the effects of Meth in animal models during different stages of addiction-like behavior on proliferation, differentiation, maturation, and survival of newly born neural progenitor cells. We will then discuss evidence for the contribution of adult neurogenesis in context-driven Meth-seeking behavior in animal models. These findings from interdisciplinary studies suggest that a subset of newly born GCNs contribute to context-driven Meth-seeking in Meth addicted animals.

References

Oct 15, 1978·The Journal of Comparative Neurology·L W SwansonW M Cowan
Jan 1, 1992·Behavioral and Neural Biology·H EichenbaumN J Cohen
Jan 1, 1989·Annual Review of Medicine·F H Gawin, E H Ellinwood
Jun 1, 1965·The Journal of Comparative Neurology·J Altman, G D Das
Apr 1, 1966·Acta Physiologica Scandinavica·P AndersenP E Voorhoeve
Jun 24, 1982·Nature·R G MorrisJ O'Keefe
May 19, 1998·Journal of Psychopharmacology·G F KoobF Weiss
Oct 13, 1998·Neuron·G F KoobF E Bloom
Nov 11, 1998·Nature Medicine·P S ErikssonF H Gage
Nov 13, 1998·Current Opinion in Neurobiology·H A Cameron, R McKay
Nov 11, 1999·Proceedings of the National Academy of Sciences of the United States of America·H van PraagF H Gage
Feb 17, 2000·Annals of the New York Academy of Sciences·G F Koob
May 2, 2000·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·M A SuttonD W Self
Jul 27, 2000·Annals of the New York Academy of Sciences·G F Koob
Jun 27, 2001·Nature Neuroscience·G Aston-JonesM L Oshinsky
Aug 27, 2002·Neuron·Neil BurgessJohn O'Keefe
Oct 29, 2002·Psychopharmacology·Yavin ShahamJane Stewart
Dec 7, 2002·Nature Neuroscience·Karen LaiDavid V Schaffer
Apr 30, 2003·The Journal of Comparative Neurology·Alexandre G DayerHeather A Cameron
Feb 1, 1957·Journal of Neurology, Neurosurgery, and Psychiatry·W B SCOVILLE, B MILNER
Jan 1, 1961·Acta Physiologica Scandinavica·P ANDERSENB R KAADA
Oct 2, 2003·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·Jean Lud CadetXiaolin Deng
Oct 24, 2003·The Journal of Comparative Neurology·Jason P BrownH Georg Kuhn
Dec 24, 2003·Journal of Neurochemistry·James E SmithConchita Co
Apr 27, 2004·Nature·Christoph Schmidt-HieberJosef Bischofberger
Jun 24, 2004·Journal of Neuroscience Research·Christiana M Cooper-KuhnH Georg Kuhn
Jun 26, 2004·Annual Review of Neuroscience·Larry R SquireRobert E Clark
Jul 20, 2004·Nature Genetics·Lei CaoMatthew J During
Feb 19, 2005·Neurobiology of Aging·Paul MohapelOlle Lindvall
Mar 25, 2005·Physiological Reviews·Djoher Nora AbrousMichel Le Moal
Aug 2, 2005·The American Journal of Psychiatry·Peter W Kalivas, Nora D Volkow
Nov 4, 2005·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·M Soledad EspósitoAlejandro F Schinder
Mar 23, 2006·Psychopharmacology·Osamu KitamuraLuigi Pulvirenti
May 17, 2006·Proceedings of the National Academy of Sciences of the United States of America·Juan M EncinasGrigori Enikolopov

❮ Previous
Next ❯

Citations

Jan 4, 2020·Neurotherapeutics : the Journal of the American Society for Experimental NeuroTherapeutics·Bhavani KashyapWilliam H Frey Ii
Jul 30, 2020·Stem Cells and Development·Rui S RodriguesSara Xapelli

❮ Previous
Next ❯

Software Mentioned

MethSA
Sholl

Related Concepts

Related Feeds

Adult Stem Cells

Adult stem cells reside in unique niches that provide vital cues for their survival, self-renewal, and differentiation. They hold great promise for use in tissue repair and regeneration as a novel therapeutic strategies. Here is the latest research.

Addiction

This feed focuses mechanisms underlying addiction and addictive behaviour including heroin and opium dependence, alcohol intoxication, gambling, and tobacco addiction.

Related Papers

Journal of Experimental Neuroscience
Chitra D MandyamYoshio Takashima
Molecular Neurobiology
Itaru Imayoshi, Ryoichiro Kageyama
TheScientificWorldJournal
Yue ZhangPing-Yee Law
© 2022 Meta ULC. All rights reserved