The Role of HIV in the Household Introduction and Transmission of Influenza in an Urban Slum, Nairobi, Kenya, 2008-2011

The Journal of Infectious Diseases
Michael C JuddJoshua A Mott

Abstract

Little is known about how human immunodeficiency virus (HIV) infection affects influenza transmission within homes in sub-Saharan Africa. We used respiratory illness surveillance and HIV testing data gathered in Kibera, an urban slum in Nairobi, Kenya, to examine the impact of HIV status on (1) introducing influenza to the home and (2) transmitting influenza to household contacts. While HIV status did not affect the likelihood of being an influenza index case, household contacts of HIV-infected influenza index cases had twice the risk of developing secondary influenza-like illness than contacts of HIV-negative index cases. HIV-infected influenza index cases may facilitate transmission of influenza within the home.

References

Nov 28, 2015·Trends in Microbiology·Tim K TsangBenjamin J Cowling
Dec 12, 2018·The American Journal of Tropical Medicine and Hygiene·Andrea G BuchwaldMilagritos D Tapia

Citations

Jan 13, 1989·JAMA : the Journal of the American Medical Association·J P Cohen, C Macauley
May 22, 2001·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·A D FineK Fukuda
May 15, 2003·American Journal of Epidemiology·Louise-Anne McNuttJean Paul Hafner
Jul 6, 2006·JAMA : the Journal of the American Medical Association·Bridget M Kuehn
Jan 31, 2008·American Journal of Epidemiology·Fabrice CarratAlain-Jacques Valleron
Jun 19, 2010·The New England Journal of Medicine·Benjamin J CowlingJoseph S M Peiris
Feb 2, 2011·Proceedings of the National Academy of Sciences of the United States of America·Simon CauchemezPennsylvania H1N1 working group
Oct 19, 2012·Journal of Acquired Immune Deficiency Syndromes : JAIDS·Warren DalalRebecca Bunnell
Nov 28, 2012·The Journal of Infectious Diseases·Mark A KatzRobert F Breiman

Related Concepts

Influenza-like Illness
Virus Diseases
Human Immunodeficiency Virus Test
Influenza virus vaccine
Influenza
Home Environment
HIV Infections
Influenza A virus
Slums
Disease Transmission

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