The Role of HIV in the Household Introduction and Transmission of Influenza in an Urban Slum, Nairobi, Kenya, 2008-2011

The Journal of Infectious Diseases
Michael C JuddJoshua A Mott


Little is known about how human immunodeficiency virus (HIV) infection affects influenza transmission within homes in sub-Saharan Africa. We used respiratory illness surveillance and HIV testing data gathered in Kibera, an urban slum in Nairobi, Kenya, to examine the impact of HIV status on (1) introducing influenza to the home and (2) transmitting influenza to household contacts. While HIV status did not affect the likelihood of being an influenza index case, household contacts of HIV-infected influenza index cases had twice the risk of developing secondary influenza-like illness than contacts of HIV-negative index cases. HIV-infected influenza index cases may facilitate transmission of influenza within the home.


Nov 28, 2015·Trends in Microbiology·Tim K TsangBenjamin J Cowling
Dec 12, 2018·The American Journal of Tropical Medicine and Hygiene·Andrea G BuchwaldMilagritos D Tapia


Jan 13, 1989·JAMA : the Journal of the American Medical Association·J P Cohen, C Macauley
May 22, 2001·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·A D FineK Fukuda
May 15, 2003·American Journal of Epidemiology·Louise-Anne McNuttJean Paul Hafner
Jul 6, 2006·JAMA : the Journal of the American Medical Association·Bridget M Kuehn
Jan 31, 2008·American Journal of Epidemiology·Fabrice CarratAlain-Jacques Valleron
Jun 19, 2010·The New England Journal of Medicine·Benjamin J CowlingJoseph S M Peiris
Feb 2, 2011·Proceedings of the National Academy of Sciences of the United States of America·Simon CauchemezPennsylvania H1N1 working group
Oct 19, 2012·Journal of Acquired Immune Deficiency Syndromes : JAIDS·Warren DalalRebecca Bunnell
Nov 28, 2012·The Journal of Infectious Diseases·Mark A KatzRobert F Breiman

Related Concepts

Influenza-like Illness
Virus Diseases
Human Immunodeficiency Virus Test
Influenza virus vaccine
Home Environment
HIV Infections
Influenza A virus
Disease Transmission

Trending Feeds


Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Synapse Loss as Therapeutic Target in MS

As we age, the number of synapses present in the human brain starts to decline, but in neurodegenerative diseases this occurs at an accelerated rate. In MS, it has been shown that there is a reduction in synaptic density, which presents a potential target for treatment. Here is the latest research on synapse loss as a therapeutic target in MS.

Artificial Intelligence in Cardiac Imaging

Artificial intelligence (ai) techniques are increasingly applied to cardiovascular (cv) medicine in cardiac imaging analysis. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

Social Learning

Social learning involves learning new behaviors through observation, imitation and modeling. Follow this feed to stay up to date on the latest research.

Cell Atlas of the Human Eye

Constructing a cell atlas of the human eye will require transcriptomic and histologic analysis over the lifespan. This understanding will aid in the study of development and disease. Find the latest research pertaining to the Cell Atlas of the Human Eye here.

Single Cell Chromatin Profiling

Techniques like ATAC-seq and CUT&Tag have the potential to allow single cell profiling of chromatin accessibility, histones, and TFs. This will provide novel insight into cellular heterogeneity and cell states. Discover the latest research on single cell chromatin profiling here.

Genetic Screens in iPSC-derived Brain Cells

Genetic screening is a critical tool that can be employed to define and understand gene function and interaction. This feed focuses on genetic screens conducted using induced pluripotent stem cell (iPSC)-derived brain cells.