PMID: 11930583Apr 5, 2002Paper

The role of human papillomavirus in screening for cervical cancer

Journal of the American Academy of Nurse Practitioners
S E McFadden, L Schumann

Abstract

To review the options for effectively screening for cervical cancer, including human papilloma virus (HPV) identification, cytologic screening, colposcopy, or a combination approach. Current pathophysiology, diagnostic criteria, treatment approaches, and patient preparation and education related to cervical cancer screening and prevention are also included. Comprehensive review of current literature, including research and review articles. Because the Papanicolau (Pap) smear is a screening tool, not a diagnostic tool, further studies must be done to identify the actual nature of discovered abnormalities. Of particular concern is the classification of atypical squamous cells of undetermined significance (ASCUS), which may simply indicate inflammation, or may be the first indicator of serious pathology. Following ASCUS Pap smears with HPV screening will allow for a clarification of the best approach to treatment. A screening algorithm supported by a review of the literature is proposed. Cervical cancer is a preventable disease caused by certain forms of HPV. Current screening protocols are based on the use of the Pap smear; and in areas where this test is routine and available, morbidity and mortality rates have dropped dramatica...Continue Reading

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Citations

Jan 8, 2004·Journal of Midwifery & Women's Health·Molly C Fey, Margaret W Beal
Jun 1, 2010·Journal of Women's Health·Kristin M WallR Sue Day
Aug 5, 2003·Journal of Biochemistry and Molecular Biology·Cui-hua LiuWen-ling Zheng
Apr 28, 2004·Clinical Journal of Oncology Nursing·Diane Reynolds
Aug 1, 2010·Journal of Investigative and Clinical Dentistry·Shahrokh EsfandiariJocelyne Feine
Jul 14, 2006·Emerging Infectious Diseases·Siobhán M O'ConnorJames M Hughes
Jun 27, 2020·International Journal of Cancer. Journal International Du Cancer·Joseph E TotaEduardo L Franco
Jun 23, 2011·Psycho-oncology·Mélanie DroletJames A Mansi
Feb 16, 2013·Biomedical Optics Express·Xue Zhe LiSeung-Yop Lee
Jan 1, 2008·OR Spectrum : Quantitative Approaches in Management·Kwangsoo Kim, Hong Seo Ryoo

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