The role of indocyanine green videoangiography with FLOW 800 analysis for the surgical management of central nervous system tumors: an update

Neurosurgical Focus
Francesco AcerbiPaolo Ferroli

Abstract

OBJECTIVE Indocyanine green videoangiography (ICG-VA) is an intraoperative technique used to highlight vessels in neurovascular surgery. Its application in the study of the vascular pathophysiology in CNS tumors and its role in their surgical management are still rather limited. A recent innovation of ICG-VA (i.e., the FLOW 800 algorithm integrated in the surgical microscope) allows a semiquantitative evaluation of cerebral blood flow. The aim of this study was to evaluate for the first time the systematic application of ICG-VA and FLOW 800 analysis during surgical removal of CNS tumors. METHODS Between May 2011 and December 2017, all cases in which ICG-VA and FLOW 800 analysis were used at least one time before, during, or after the tumor resection, and in which surgical videos were available, were retrospectively reviewed. Results of the histological analysis were analyzed together with the intraoperative ICG-VA with FLOW 800 in order to investigate the tumor-related videoangiographic features. RESULTS Seventy-one patients who underwent surgery for cerebral and spinal tumors were intraoperatively analyzed using ICG-VA with FLOW 800, either before or after tumor resection, for a total of 93 videoangiographic studies. The histo...Continue Reading

References

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Citations

Jan 22, 2020·Journal of Neurosurgical Sciences·Giuseppe La RoccaGiovanni Sabatino
Jan 22, 2020·Journal of Neurosurgical Sciences·Jorge Navarro-BonnetAlfredo Quinones-Hinojosa
Dec 7, 2018·Neurosurgical Review·Bianca M DijkstraRob J M Groen
Sep 3, 2019·Frontiers in Oncology·Daniel ValliMark C Preul

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Software Mentioned

FLOW 800
FLOW
ICG
VA

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