The role of job strain in understanding midlife common mental disorder: a national birth cohort study

The Lancet. Psychiatry
Samuel B HarveyArnstein Mykletun

Abstract

Long-standing concerns exist about reverse causation and residual confounding in the prospective association between job strain and risk of future common mental disorders. We aimed to address these concerns through analysis of data collected in the UK National Child Development Study, a large British cohort study. Data from the National Child Development Study (n=6870) were analysed by use of multivariate logistic regression to investigate the prospective association between job strain variables at age 45 years and risk of future common mental disorders at age 50 years, controlling for lifetime psychiatric history and a range of other possible confounding variables across the lifecourse. Population attributable fractions were calculated to estimate the public health effect of job strain on midlife mental health. In the final model, adjusted for all measured confounders, high job demands (odds ratio 1·70, 95% CI 1·25-2·32; p=0·0008), low job control (1·89, 1·29-2·77; p=0·0010), and high job strain (2·22, 1·59-3·09; p<0·0001) remained significant independent predictors of future onset of common mental disorder. If causality is assumed, our findings suggest that 14% of new cases of common mental disorder could have been prevented ...Continue Reading

Citations

May 14, 2019·Annals of Work Exposures and Health·Jonathan K FanPeter M Smith
Sep 12, 2019·Social Psychiatry and Psychiatric Epidemiology·Annemette Coop Svane-PetersenIda E H Madsen
Aug 20, 2020·Social Psychiatry and Psychiatric Epidemiology·Liana S LeachLyndall Strazdins
Mar 17, 2020·Frontiers in Psychiatry·Johannes Siegrist, Natalia Wege
Aug 17, 2021·The Journals of Gerontology. Series B, Psychological Sciences and Social Sciences·Mirkka LahdenperäSari Stenholm

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