The Role of Lifestyle in Male Infertility: Diet, Physical Activity, and Body Habitus

Current Urology Reports
Russell P HaydenPeter N Schlegel

Abstract

Increasing attention to primary and secondary prevention of male infertility through modifiable lifestyle factors has gained traction amongst both patients and infertility specialists. In this review, the available evidence of modifiable lifestyle choices, specifically diet, physical activity, and body habitus, are evaluated. Studies examining diet, exercise/physical activity, and body habitus are characterized by conflicting conclusions, difficult confounders, and imperfect end points to judge male reproductive potential. However, convincing trends have emerged implicating consumption of saturated fats, pesticide exposure, high intensity exercise, and extremes of body mass index as detrimental to male fertility. Data assessing modifiable risk factors and subfertility in male partners has emphasized the notion of moderation. Balancing dietary fat, moderation of physical activity, and the management of a healthy body habitus favor both improvement of semen quality and birth outcomes. These observations provide actionable data for the reproductive urologist to better counsel men presenting with infertility.

References

May 1, 1989·The British Journal of Nutrition·T HanisZ Deyl
Mar 1, 1994·Preventive Medicine·E I FlorackR Rolland
Jun 10, 2000·BJOG : an International Journal of Obstetrics and Gynaecology·M G Katz, B Vollenhoven
Oct 17, 2001·Medical Hypotheses·D GanmaaA Sato
Oct 31, 2001·The American Journal of Clinical Nutrition·J W AndersonC L Wood
Jan 17, 2002·The Journal of Urology·Jay D Raman, Peter N Schlegel
May 16, 2002·Fertility and Sterility·Ira D SharlipRichard Sadovsky
Dec 26, 2002·Journal of Occupational and Environmental Medicine·Einat K SheinerIlana Shoham-Vardi
Dec 25, 2004·Human Reproduction·Antonio Scotto di FregaMartin Wilding
Apr 14, 2006·The New England Journal of Medicine·Dariush MozaffarianWalter C Willett
Jul 20, 2007·Human Reproduction·Ruby H N NguyenDonna D Baird
Nov 6, 2007·Current Opinion in Endocrinology, Diabetes, and Obesity·Anne B Loucks
Mar 4, 2008·Fertility and Sterility·Jaime MendiolaRafael Bernabeu
Nov 18, 2008·Fertility and Sterility·Diana VaamondeSergio Carlos Oehninger
Feb 21, 2009·Human Reproduction·M VujkovicR P M Steegers-Theunissen
Mar 21, 2009·International Journal of Sports Medicine·M GrandysJ A Zoladz
Apr 11, 2009·The Journal of Biological Chemistry·Kelly L WeaverFloyd H Chilton
Apr 11, 2009·Obesity·Natalie S The, Penny Gordon-Larsen
Aug 12, 2009·Clinical Nutrition : Official Journal of the European Society of Parenteral and Enteral Nutrition·Mohammad Reza SafarinejadMajid Ali Asgari
Oct 16, 2009·Human Reproduction·Lauren A WiseElizabeth E Hatch
Mar 27, 2010·American Journal of Epidemiology·Tina Kold JensenNiels Jørgensen
Jul 8, 2010·Journal of Human Reproductive Sciences·Ghasem SakiOzra Allah Vaysi
Jul 17, 2010·Journal of Assisted Reproduction and Genetics·Julia KeltzAlex J Polotsky
Sep 9, 2010·American Journal of Physiology. Endocrinology and Metabolism·Mark J DekkerKhosrow Adeli
Dec 3, 2010·Fertility and Sterility·Lauren A WiseStacey A Missmer
Oct 25, 2011·Reproductive Biomedicine Online·A G ShayebS Bhattacharya
Jan 12, 2012·European Journal of Applied Physiology·Diana VaamondeRicardo Vaamonde-Lemos
Mar 14, 2012·Archives of Internal Medicine·Nathalie SermondadeUNKNOWN Obesity-Fertility Collaborative Group
Mar 15, 2012·Human Reproduction·Jill A AttamanJorge E Chavarro
Apr 27, 2012·Reproductive Sciences·Leonardo Oliveira ReisAdriano Fregonesi
Jun 5, 2012·Asian Journal of Andrology·Mohammad Reza Safarinejad, Shiva Safarinejad
Aug 14, 2012·Human Reproduction·Audrey J GaskinsJorge E Chavarro
Sep 18, 2012·Biochimie·Gary J HausmanClay A Lents
Nov 14, 2012·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·C FortesC Aprea
Feb 6, 2013·British Journal of Sports Medicine·Audrey Jane GaskinsJorge E Chavarro
Mar 26, 2013·Reproductive Biology·David LandryLuc J Martin
Jan 15, 2014·Human Reproduction·Jorge E ChavarroAlberto M Torres-Cantero
Mar 19, 2014·Fertility and Sterility·Myriam C AfeicheJorge E Chavarro
Apr 25, 2014·Asian Journal of Andrology·Lise ThomsenMona Bungum

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Citations

Sep 7, 2018·Molecular Reproduction and Development·Jay SchinfeldAlexander J Travis
Oct 23, 2018·Diabetes·Kristin I StanfordLaurie J Goodyear
Jul 13, 2019·Journal of Clinical Pathology·Layla ThurstonWaljit S Dhillo
Jan 18, 2020·JAMA Network Open·Tina Kold JensenNiels Jørgensen
Apr 25, 2020·Andrologia·Kristian Leisegang, Sulagna Dutta
Aug 29, 2018·Nutrients·Anna DanielewiczMariusz Przybyłowicz
Feb 14, 2021·Urologia·Riccardo BientinesiEmilio Sacco
Dec 2, 2020·International Journal of Endocrinology and Metabolism·Mina Amiri, Fahimeh Ramezani Tehrani
Nov 6, 2020·International Journal of Reproductive Medicine·Richard Michael BlayBenjamin Arko-Boham
Mar 10, 2021·Andrologia·Fernando LopesRosário Pinto-Leite

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