The role of liquid-phase microextraction techniques in bioanalysis

Bioanalysis
Mário BarrosoJoão Queiroz

Abstract

Sample preparation is one of the most challenging tasks in laboratories, particularly in what concerns biological specimens, since they cannot be directly analyzed. A considerable amount of time and effort is spent in the extraction of the analytes and their concentration in a solvent that is compatible with analytical instrumentation. Several approaches can be used for this purpose, and one of the most used worldwide is LLE. This article outlines how the miniaturized approach of LLE - liquid-phase microextraction - was developed. The different types of liquid-phase microextraction and their applications are also discussed.

References

Feb 1, 2005·Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences·Stig Pedersen-Bjergaard, Knut Einar Rasmussen
Apr 1, 2006·Journal of Chromatography. a·Mohammad RezaeeSana Berijani
Nov 26, 2009·Journal of Chromatography. a·Michael A JeannotJohn M Kokosa
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Aug 11, 2012·Bioanalysis·Mário BarrosoEugenia Gallardo

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Citations

Jul 13, 2019·International Journal of Legal Medicine·Sofia SoaresEugenia Gallardo
May 1, 2021·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Samir M AhmadJosé M F Nogueira
Jul 27, 2021·Drug Metabolism Reviews·Aarzoo ThakurChukwunonso K Nwabufo

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