The role of liver resection at the time of secondary cytoreduction in patients with recurrent ovarian cancer

International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society
Valentin KolevKonstantin Zakashansky

Abstract

The aim of this study is to determine the role of liver metastatectomy in the morbidity and survival of patients with recurrent ovarian carcinoma. We retrospectively reviewed the records of all patients who had undergone hepatic resection for liver metastases from ovarian carcinoma at the time of cytoreductive surgery at our institution from 1988 to 2012. The Kaplan-Meier method was used for survival analysis. A total of 76 patients met the inclusion criteria and had undergone liver resection as part of cytoreductive surgery for ovarian carcinoma during the study period. Of these 76 patients, 27 underwent liver resection at the time of secondary cytoreduction, and these patients that are the focus of this analysis. Median overall survival for the study group from the time of diagnosis to the last follow-up or death was 56 months (range, 12-249 months). Twenty died of the disease with an overall median survival of 12 months from the time of the liver resection (2-190 months), and 7 patients were alive with the disease at the time of the last follow-up. Based on Kaplan-Meier survival analysis, the factors associated with the longest survival after the liver resection (2-190 months) were the interval from the primary surgery of le...Continue Reading

References

Mar 1, 1978·American Journal of Surgery·J H Foster
Jan 1, 1995·CA: a Cancer Journal for Clinicians·Y FongA M Cohen
Jul 1, 1997·Gynecologic Oncology·D S ChiR R Barakat
Jan 7, 2000·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·F M MuggiaJ M Small
Apr 16, 2003·Gynecologic Oncology·Melissa A MeridethKarl C Podratz
Mar 1, 1963·Cancer·A BRUNSCHWIG
Nov 6, 2003·Gynecologic Oncology·Sam S YoonDennis S Chi
Oct 14, 2005·Current Oncology Reports·Teresa P Díaz-Montes, Robert E Bristow
Oct 22, 2008·Gynecologic Oncology·Robert E BristowDennis S Chi
Sep 11, 2012·The Oncologist·René AdamUNKNOWN Jean-Nicolas Vauthey of the EGOSLIM (Expert Group on OncoSurgery management of LIver Metastases) group
Jan 22, 2013·CA: a Cancer Journal for Clinicians·Rebecca SiegelAhmedin Jemal

❮ Previous
Next ❯

Citations

Dec 15, 2015·Journal of Cancer Research and Clinical Oncology·Maria Luisa GasparriAndrea Papadia
Jun 23, 2016·Gynecologic Oncology Research and Practice·Neville F Hacker, Archana Rao
Nov 23, 2011·European Journal of Oncology Nursing : the Official Journal of European Oncology Nursing Society·Mary RyanJudith Fethney
Oct 13, 2018·Journal of Hepato-biliary-pancreatic Sciences·Keiji SanoUNKNOWN Japanese Society of Hepato-Biliary-Pancreatic Surgery
Apr 16, 2020·Journal of Gynecologic Surgery·Jorge Luna-AbantoVladimir Villoslada Terrones
Mar 7, 2017·World Journal of Hepatology·Nobuyuki Takemura, Akio Saiura
Nov 18, 2020·Journal of Hepato-biliary-pancreatic Sciences·Masakazu YamamotoTadahiro Takada

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.