The Role of Long Non-coding RNAs in the Pathogenesis of RA, SLE, and SS

Frontiers in Medicine
Yunzhen GaoJunfeng Zheng

Abstract

Rheumatoid diseases are a group of systemic autoimmune diseases which affect multiple organs with largely unknown etiology. In the past decade, long non-coding RNAs (lncRNAs) have emerged as important regulators of biological processes and contribute deeply to immune cell development and immune responses. Substantial evidences have been accumulated showing that LncRNAs involved in the pathogenesis of the rheumatoid diseases, including rheumatoid arthritis (RA), systemic lupus erythematosus (SLE) and Sjögren's syndrome (SS). In this review, we summarize literature combined with bioinformatics methods to analyze the unique and common lncRNAs patterns in rheumatoid diseases and try to reveal the important function of lncRNAs in RA, SLE and SS.

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Citations

Jun 26, 2020·Biomolecules·Mohammad TaheriSoudeh Ghafouri-Fard
Nov 28, 2020·BMC Genomics·Liza C GershonyAnita M Oberbauer
Feb 3, 2021·International Journal of Molecular Sciences·Elisa GnodiDonatella Barisani
Nov 24, 2020·Translational Research : the Journal of Laboratory and Clinical Medicine·Zhihong YangSuthat Liangpunsakul
Feb 19, 2021·PloS One·Yu-Feng QingQuan-Bo Zhang
Aug 5, 2021·Journal of Cell Communication and Signaling·Anastasiya MuntyanuElena Netchiporouk
Jul 16, 2021·Applied Immunohistochemistry & Molecular Morphology : AIMM·Yoshiro HoraiAtsushi Kawakami
Jan 23, 2022·Inflammation·Wangdong XuAnfang Huang

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Methods Mentioned

BETA
protein folding
acetylation
ubiquitination
ESR
chip

Software Mentioned

GENCODE
cytoscape
STRING
lncRInter
Venny webset
lncRInter websver

Related Concepts

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