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The role of mannose-binding lectin gene polymorphisms in susceptibility to HIV-1 infection in Southern Brazilian patients

AIDS

Dec 31, 2010

Gabriela Kniphoff Da SilvaJ A B Chies

Abstract

This study investigates the role of mannose-binding lectin (MBL) in the susceptibility to HIV-1 infection analyzing polymorphisms located at the MBL2 promoter and exon 1 regions. The prevalence of MBL2 variant alleles was investigated in 410 HIV-1-infected patients from the South Brazil...read more

Mentioned in this Paper

Gene Polymorphism
Real-Time Polymerase Chain Reaction
CD206 antigen
Mannose Binding Lectin
Exons
Hormone Receptors, Cell Surface
Promoter
HIV Infections
MBL2 protein, human
MBL2 gene
Paper Details
References
  • References47
  • Citations11
12345
  • References47
  • Citations11
12

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The role of mannose-binding lectin gene polymorphisms in susceptibility to HIV-1 infection in Southern Brazilian patients

AIDS

Dec 31, 2010

Gabriela Kniphoff Da SilvaJ A B Chies

PMID: 21192229

DOI: 10.1097/qad.0b013e328342fef1

Abstract

This study investigates the role of mannose-binding lectin (MBL) in the susceptibility to HIV-1 infection analyzing polymorphisms located at the MBL2 promoter and exon 1 regions. The prevalence of MBL2 variant alleles was investigated in 410 HIV-1-infected patients from the South Brazil...read more

Mentioned in this Paper

Gene Polymorphism
Real-Time Polymerase Chain Reaction
CD206 antigen
Mannose Binding Lectin
Exons
Hormone Receptors, Cell Surface
Promoter
HIV Infections
MBL2 protein, human
MBL2 gene

Similar Papers Found In These Feeds

Complement Pathway: Mannose-Binding Lectin

The Mannose-Binding Lectin Complement Pathway is activated when mannose-binding lectin binds to mannose found on the surface of pathogens. Subsequent complement activation is similar to the classical complement pathway, but without the need for antigen-antibody complexes. Discover the latest research here.

AIDS Malignancies

HIV infection increases the risk of non-communicable diseases common in the aged, including cardiovascular disease, neurocognitive decline, non-aids malignancies, osteoporosis, and frailty. Discover the latest research in AIDS malignancies.

Related Papers

Paper Details
References
  • References47
  • Citations11
12345
  • References47
  • Citations11
12
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