The Role of Maternal Thyroid Hormones in Avian Embryonic Development

Frontiers in Endocrinology
Veerle M Darras

Abstract

During avian embryonic development, thyroid hormones (THs) coordinate the expression of a multitude of genes thereby ensuring that the correct sequence of cell proliferation, differentiation and maturation is followed in each tissue and organ. Although THs are needed from the start of development, the embryonic thyroid gland only matures around mid-incubation in precocial birds and around hatching in altricial species. Therefore, maternal THs deposited in the egg yolk play an essential role in embryonic development. They are taken up by the embryo throughout its development, from the first day till hatching, and expression of TH regulators such as distributor proteins, transporters, and deiodinases in the yolk sac membrane provide the tools for selective metabolism and transport starting from this level. TH receptors and regulators of local TH availability are expressed in avian embryos in a dynamic and tissue/cell-specific pattern from the first stages studied, as shown in detail in chicken. Maternal hyperthyroidism via TH supplementation as well as injection of THs into the egg yolk increase TH content in embryonic tissues while induction of maternal hypothyroidism by goitrogen treatment results in a decrease. Both increase a...Continue Reading

References

Nov 1, 1985·Poultry Science·V L Christensen
May 1, 1985·General and Comparative Endocrinology·F M McNabb, M F Cheng
Aug 1, 1997·General and Comparative Endocrinology·C M Wilson, F M McNabb
Jun 13, 1998·Developmental Biology·F Flamant, J Samarut
Apr 13, 2000·Brain Research. Brain Research Reviews·J Mey, S Thanos
Jul 12, 2002·Journal of Medicinal Chemistry·Ngoc-Ha NguyenThomas S Scanlan
Sep 13, 2003·The Journal of Clinical Endocrinology and Metabolism·S ChanM D Kilby
Nov 20, 2003·Nature Neuroscience·Akihiro NishidaTakahisa Furukawa
Aug 2, 2005·Annals of the New York Academy of Sciences·Ton G G Groothuis, Nikolaus von Engelhardt
Feb 21, 2006·Thyroid : Official Journal of the American Thyroid Association·Veerle M DarrasSerge Van der Geyten
Apr 1, 2006·Developmental Biology·Raman M DasStuart A Wilson
Aug 1, 2007·Proceedings of the National Academy of Sciences of the United States of America·Yangu ZhaoHeiner Westphal
Nov 9, 2007·Cellular and Molecular Life Sciences : CMLS·B GerebenA C Bianco
Feb 2, 2008·BMC Genomics·Xianyao LiHuaijun Zhou
Oct 22, 2008·Molecular and Cellular Endocrinology·Vanya ShahPaul Webb
Dec 10, 2008·General and Comparative Endocrinology·Veerle M DarrasGeert E Reyns
Jul 29, 2010·Neural Development·Fatiha BoukhtoucheJean Mariani
Aug 25, 2010·Brain, Behavior and Evolution·Toru ShimizuScott A Husband
Nov 18, 2010·Gene Expression Patterns : GEP·Wataru KimuraKimiko Fukuda
Sep 5, 2012·The Journal of Clinical Investigation·Gregory A Brent
Apr 24, 2013·The Journal of Endocrinology·Stijn L J Van HerckVeerle M Darras
Apr 2, 2014·General and Comparative Endocrinology·Paula Duarte-GutermanVance L Trudeau
Apr 14, 2016·Endocrinology·Nele M A BourgeoisTheo J Visser
Oct 30, 2016·General and Comparative Endocrinology·Bin-Yan HsuTon G G Groothuis
Nov 24, 2016·The Journal of Endocrinology·Joke DelbaereVeerle M Darras

❮ Previous
Next ❯

Citations

May 24, 2019·Acta Physiologica·Jean-David GothiéSylvie Remaud
Jan 30, 2020·International Journal of Developmental Neuroscience : the Official Journal of the International Society for Developmental Neuroscience·Dena A-E MohammedR G Ahmed
Oct 26, 2020·Endocrinology·Leena H ShewadeDaniel R Buchholz
May 31, 2021·Trends in Ecology & Evolution·Mylene M MarietteKatherine L Buchanan
Jun 29, 2021·General and Comparative Endocrinology·C LamberigtsJ Buyse

❮ Previous
Next ❯

Methods Mentioned

BETA
fluorescence activated cell sorting

Software Mentioned

Ingenuity Pathway Analysis

Related Concepts

Related Feeds

Cell Migration

Cell migration is involved in a variety of physiological and pathological processes such as embryonic development, cancer metastasis, blood vessel formation and remoulding, tissue regeneration, immune surveillance and inflammation. Here is the latest research.