The role of microRNAs in colorectal cancer

Journal of Genetics and Genomics = Yi Chuan Xue Bao
Mao Liu, Huiping Chen

Abstract

MicroRNAs are small non-coding RNAs which regulate gene expression in a post-transcriptional manner. Although the first study was published about 15 years ago, knowledge about their role in regulation of cell proliferation, differentiation, apoptosis and immunity has been greatly advanced recently. Their association with formation, angiogenesis, metastasis and chemotherapy resistance of tumors has become one of the core issues in epigenetics of cancer. Here, we summarize the latest findings concerning microRNAs involved in different signal pathways leading to colorectal cancer, introduce some new potential microRNAs as biomarkers in diagnosis and prognosis, and analyze its application in the treatment of cancer.

References

Apr 1, 1997·Proceedings of the National Academy of Sciences of the United States of America·M TsujiiR N DuBois
Nov 24, 1999·The Journal of Experimental Medicine·J D HudsonD H Beach
Jun 30, 2000·The New England Journal of Medicine·G SteinbachG Kelloff
Oct 27, 2001·Science·M Lagos-QuintanaT Tuschl
Oct 27, 2001·Science·R C Lee, V Ambros
Mar 20, 2002·Nature Reviews. Cancer·R FoddeH Clevers
May 16, 2003·Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc·Hugues LegendreRobert Kiss
May 4, 2005·Cancer Research·Richard I Gregory, Ramin Shiekhattar
Jun 10, 2005·Nature·Jun LuTodd R Golub
Nov 16, 2005·Gastroenterology·Jonathan M WilsonMark A Hull
Feb 24, 2006·Nature Reviews. Molecular Cell Biology·Jean Paul Thiery, Jonathan P Sleeman
May 3, 2006·Biological & Pharmaceutical Bulletin·Yukihiro AkaoTomoki Naoe
Aug 1, 2006·Nature Genetics·Michael DewsAndrei Thomas-Tikhonenko
May 1, 2007·Nature Medicine·Alessandra CarèGianluigi Condorelli
Jun 30, 2007·Proceedings of the National Academy of Sciences of the United States of America·Scott ShellMarcus E Peter
Sep 19, 2007·Proceedings of the National Academy of Sciences of the United States of America·Hiroshi TazawaHitoshi Nakagama
Sep 25, 2007·Proceedings of the National Academy of Sciences of the United States of America·Muller FabbriCarlo M Croce
Apr 23, 2008·American Journal of Clinical Pathology·Hanna LeeHoguen Kim
Aug 5, 2008·Cancer Research·Troels SchepelerClaus L Andersen
Oct 9, 2008·Nature Medicine·Victor Ambros
Mar 17, 2009·International Journal of Oncology·Kazuo MotoyamaMasaki Mori
Jul 18, 2009·Biochemical and Biophysical Research Communications·Xian WangJoseph J Y Sung
Jul 18, 2009·Nature Reviews. Genetics·Brian D Brown, Luigi Naldini

❮ Previous
Next ❯

Citations

Feb 9, 2011·Parasitology Research·Saleh Al-QuraishyMohamed Abdel Monam Dkhil
Jun 26, 2013·Cancer Letters·Yanyan LiYanling Kong
Sep 23, 2008·BMC Public Health·Antonio FedericiUNKNOWN Colon-Rectal Cancer Screening Working Group
Jun 16, 2012·Yi chuan = Hereditas·Li-Hua YangZhao-Hui Gong
Jul 21, 2011·World Journal of Clinical Oncology·Oscar J CorderoF Javier Rodriguez-Berrocal
Apr 15, 2011·Journal of Biomedicine & Biotechnology·Lucia MiglioreFabio Coppedè
Aug 22, 2014·BioMed Research International·Giuseppina Della Vittoria ScarpatiChiara Carlomagno
Apr 27, 2013·Journal of Genetics and Genomics = Yi Chuan Xue Bao·Liming Ma, Lianghu Qu
Apr 7, 2012·The Journal of Surgical Research·Alexander M RiordanGregory D Kennedy
Oct 21, 2015·Genomics Data·Lisa PerilliPaola Zanovello
Oct 25, 2011·International Journal of Cancer. Journal International Du Cancer·Yongxi SongHuimian Xu
Jan 24, 2012·Clinical Genetics·F Migheli, L Migliore
Mar 23, 2011·The Annals of Thoracic Surgery·Andrew FeberVirginia R Litle
Mar 5, 2015·Clinics and Research in Hepatology and Gastroenterology·Iman RamzyZienab A Soliman
May 6, 2015·Translational Research : the Journal of Laboratory and Clinical Medicine·Rajagopal N Aravalli, Clifford J Steer
Feb 25, 2014·Biochimica Et Biophysica Acta·Aristeidis G VaiopoulosAthanasios G Papavassiliou
Oct 18, 2014·Frontiers in Genetics·Marah C RuntschRyan M O'Connell
Jan 21, 2017·International Journal of Molecular Sciences·Inés MármolMaría Jesús Rodriguez Yoldi
Apr 3, 2010·Journal of General Internal Medicine·Heather J BaerJennifer S Haas
Apr 6, 2018·Scientific Reports·Sneha MishraNagalingam R Sundaresan
Apr 6, 2013·British Journal of Cancer·E HofsliL Thommesen
Sep 13, 2019·IUBMB Life·Noha G Bader El DinMostafa El Awady
Aug 25, 2015·Journal of Experimental & Clinical Cancer Research : CR·Zanxi FangZhong-Ying Zhang
Jan 18, 2018·Oncotarget·Qixin LengFeng Jiang
Aug 16, 2016·Journal of Hematology & Oncology·Yu-Xiao LiuChun-Ji Gao
Jan 3, 2019·Cytotechnology·Gizem Ors-KumogluCigir Biray-Avci
Sep 28, 2016·World Journal of Gastroenterology : WJG·Ferenc SiposGyörgyi Műzes
Jun 3, 2017·BioMed Research International·María Antonia LizarbeJavier Turnay
Oct 25, 2014·Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology·Stephanie L SchmitStephen B Gruber

❮ Previous
Next ❯

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