The role of milk sialyllactose in intestinal bacterial colonization.

Advances in Nutrition
Gisela A Weiss, Thierry Hennet

Abstract

Milk oligosaccharides influence the composition of intestinal microbiota and thereby mucosal inflammation. Some of the major milk oligosaccharides are α2,3-sialyllactose (3SL) and α2,6-sialyllactose, which are mainly produced by the sialyltransferases ST3GAL4 and ST6GAL1, respectively. Recently, we showed that mice fed milk deficient in 3SL were more resistant to dextran sulfate sodium-induced colitis. By contrast, the exposure to milk containing or deficient in 3SL had no impact on the development of mucosal leukocyte populations. Milk 3SL mainly affected the colonization of the intestine by clostridial cluster IV bacteria.

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Citations

May 16, 2012·Advances in Nutrition·Clemens KunzSharon M Donovan
May 16, 2014·Nutrition Reviews·Sandra J M ten BruggencateMargriet H C Schoterman
Aug 7, 2017·Journal of Cellular and Molecular Medicine·Jimin JeonSiyoung Yang
Sep 12, 2020·Critical Reviews in Food Science and Nutrition·Emmanuel Pérez-EscalanteLuis Guillermo González-Olivares
Aug 23, 2019·International Journal of Environmental Research and Public Health·Yonglan TianHai Huang
Jul 13, 2019·International Journal of Environmental Research and Public Health·Yonglan TianHai Huang
May 28, 2020·Frontiers in Immunology·Marit ZuurveldLinette E M Willemsen
Jan 1, 2019·Comprehensive Reviews in Food Science and Food Safety·Susana Figueroa-Lozano, Paul de Vos
Jan 31, 2021·Science Advances·Yujung Michelle LeeJanelle S Ayres
Jul 29, 2021·Pediatric Gastroenterology, Hepatology & Nutrition·Yong Joo Kim

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