PMID: 19930977Nov 26, 2009Paper

The role of MRI in breast cancer screening

Journal of the National Comprehensive Cancer Network : JNCCN
Constance D Lehman, Robert A Smith

Abstract

The 2009 NCCN Clinical Practice Guidelines in Oncology for Breast Cancer Screening and Diagnosis include significant updates for the role of MRI in screening women at increased risk for breast cancer. The NCCN now recommends considering breast MRI as an adjunct to annual mammography and clinical breast examination for women who have a BRCA1 or -2 mutation or who have a first-degree relative who has a BRCA1 or -2 mutation but who have not undergone genetic testing themselves; those who are determined to have a lifetime risk greater than 20% based on models that are highly dependent on family history; and those with a history of lobular carcinoma in situ. MRI is also recommended for patients who underwent radiation treatment to the chest between 10 and 30 years of age, and in those who carry or have a first-degree relative who carries a genetic mutation in the TP53 or PTEN genes (Li-Fraumeni, Cowden, and Bannahyan-Riley-Ruvalcaba syndromes). MRI is specifically not recommended for screening women at average risk for breast cancer. This article describes the peer-reviewed, published clinical research trials evaluating breast MRI in high-risk patients, on which the NCCN guidelines were based, and provides suggestions for future res...Continue Reading

Citations

Jul 16, 2010·Technology in Cancer Research & Treatment·Elita M DeFeo, Leo L Cheng
Mar 23, 2011·The Mount Sinai Journal of Medicine, New York·Gautam S MuralidharMia K Markey
Sep 16, 2011·Expert Review of Anticancer Therapy·Valencia King, D David Dershaw
Apr 29, 2015·Breast Cancer : the Journal of the Japanese Breast Cancer Society·Hiroaki KuriharaKenji Tamura
Mar 6, 2019·Journal of Personalized Medicine·Ava WilloughbyAmanda Ewart Toland
May 25, 2013·AJR. American Journal of Roentgenology·Constance D LehmanMitchell D Schnall
Oct 1, 2010·Journal of Magnetic Resonance Imaging : JMRI·Richard A E EddenPeter B Barker
Aug 25, 2012·Radiology·Christoph I LeeConstance D Lehman
Mar 20, 2012·Breast Cancer Research : BCR·Jennifer M Specht, David A Mankoff
May 22, 2018·The Breast Journal·Mary C WhiteDale P Sandler
Nov 5, 2010·Current Opinion in Obstetrics & Gynecology

❮ Previous
Next ❯

Related Concepts

Related Feeds

Carcinoma, Lobular

Lobular carcinoma is an invasive type of breast cancer in which lobules, areas of the breast that produce milk, undergo malignant transformation. Here is the latest research.

Breast Cancer: BRCA1 & BRCA2

Mutations involving BRCA1, found on chromosome 17, and BRCA2, found on chromosome 13, increase the risk for specific cancers, such as breast cancer. Discover the last research on breast cancer BRCA1 and BRCA2 here.

Related Papers

The Mount Sinai Journal of Medicine, New York
Laurie Margolies, Richard Ha
Journal of the National Comprehensive Cancer Network : JNCCN
Constance D LehmanStephen B Edge
Journal of the National Comprehensive Cancer Network : JNCCN
Richard L TheriaultNational Comprehensive Cancer Network
Journal of the National Comprehensive Cancer Network : JNCCN
Robert J MotzerNatiomal compresensive cancer networks
© 2022 Meta ULC. All rights reserved