The role of mucus in cough research.

Lung
Bruce K Rubin

Abstract

Cough is a defense mechanism for promoting airway hygiene when mucociliary clearance is ineffective due to increased mucus secretion, inflammation, infection, or ciliary dysfunction. Secretions can contribute to airflow limitation and chronic hypersecretion can worsen airway inflammation with retained inflammatory cells and mediators. The focus of the Second Annual Cough Conference has been on cough as a troublesome symptom; but to understand the importance and effectiveness of cough clearance, it is critical to understand airway secretions. The biophysical properties of mucus and phlegm determine how readily these secretions can be cleared by coughing.

References

Jan 1, 1985·Respiration; International Review of Thoracic Diseases·K Morgenroth, J Bolz
Mar 1, 1985·Pediatric Pulmonology·L C MarchetteA Wanner
Nov 14, 1997·JAMA : the Journal of the American Medical Association·A AnzuetoB K Rubin
Feb 19, 1999·Pediatric Pulmonology·B K Rubin
Jul 11, 2003·Chest·Chikako KishiokaBruce K Rubin
Feb 28, 2004·American Journal of Respiratory Cell and Molecular Biology·Markus O HenkeBruce K Rubin
Dec 6, 2005·Health & Social Care in the Community·Stephen AbbottSarah Cotter
Jan 20, 2006·The New England Journal of Medicine·Scott H DonaldsonRichard C Boucher
Apr 11, 2007·Paediatric Respiratory Reviews·Bruce K Rubin
Jun 3, 2008·Paediatric Respiratory Reviews·F Ratjen
Feb 10, 2009·Chest·Judith A Voynow, Bruce K Rubin
May 27, 2009·Respiratory Care·Bruce K Rubin

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Citations

Dec 3, 2010·The New England Journal of Medicine·John V Fahy, Burton F Dickey
Jun 8, 2018·Journal of Aerosol Medicine and Pulmonary Drug Delivery·Beatriz Herrero-CortinaEva Polverino
Aug 7, 2017·Expert Review of Respiratory Medicine·Michael F PapacostasSusan Hupp
Jul 15, 2021·Seminars in Respiratory and Critical Care Medicine·Gerard Muñoz Castro, Ana Balañá Corberó
Jul 14, 2021·Annual Review of Biomedical Engineering·Lydia Bourouiba

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