Abstract
Growing evidence has suggested an important role of n-3 polyunsaturated fatty acids in reducing risk of cardiovascular disease in the general population and patients with preexisting heart disease. In particular, several long-term epidemiologic studies have found an inverse association between fish consumption and risk of coronary heart disease or stroke. Two secondary prevention trials have found that increasing fish consumption or fish oil supplementation significantly reduced coronary death among patients with existing myocardial infarction. In addition, epidemiologic and clinical studies have suggested that alpha-linolenic acid (ALA), a short-chain n3-3 fatty acid from plant sources, may have similar cardiac benefits as long-chain n-3 fatty acids from fish. Potential mechanisms through which n-3 polyunsaturated fatty acids protect against CVD include their antiarrhythmic and antithrombotic effects, and improving insulin sensitivity and endothelial function. (c) 2001 Prous Science. All rights reserved.
Citations
Aug 27, 2005·Thrombosis Research·T YamashitaJ Yamamoto
Jan 16, 2013·Nutrition & Metabolism·Madelaine T CarstensEstelle V Lambert
Dec 31, 2014·International Journal of Audiology·Ulf RosenhallElisabet Rothenberg
Jul 31, 2013·Journal of Periodontal Research·D V Sculley
Mar 31, 2009·Journal of the American Dietetic Association·Natalie D RiedigerMohammed H Moghadasian
Nov 30, 2005·Nutrition, Metabolism, and Cardiovascular Diseases : NMCD·Demosthenes B PanagiotakosChristodoulos Stefanadis
Nov 1, 2005·Journal of the American Dietetic Association·Martha L DaviglusJeremiah Stamler
Jan 9, 2013·Explore : the Journal of Science and Healing·Richard Glickman-Simon, Alan Ehrlich
Sep 10, 2013·International Journal of Cardiology·Roberto Marchioli, Giacomo Levantesi
Jun 24, 2008·The American Journal of Cardiology·Bradley J WillcoxBeatriz L Rodriguez
Jul 30, 2014·The Canadian Journal of Cardiology·J George FodorBranislav Vohnout
Apr 23, 2004·American Journal of Physiology. Endocrinology and Metabolism·Amy J DavidoffJun Ren
Aug 21, 2007·Clinical Journal of the American Society of Nephrology : CJASN·Ronald J HoggUNKNOWN North American IgA Nephropathy Study Group
Oct 4, 2007·Molecular Nutrition & Food Research·Maria Annunziata CarluccioRaffaele De Caterina
Apr 28, 2005·Nutrition, Metabolism, and Cardiovascular Diseases : NMCD·J I MannUNKNOWN Diabetes and Nutrition Study Group (DNSG) of the European Association