The role of neovascularization in the survival of an arterialized venous flap

Plastic and Reconstructive Surgery
B PittetA E Cram

Abstract

This study compares survival of arterialized venous flaps placed on normal and impaired recipient beds in New Zealand White rabbit ear. Fasciocutanous flaps (4 x 5 cm) were perfused by an arteriovenous anastomosis; outflow was provided by one vein. In group 1, the arterialized venous flap was sutured into its bed on the ear; in group 2, a sheet of silicone was placed between the flap and the ear, providing an experimentally impaired recipient bed. Flap survival was expressed as a percentage of the total flap surface by means of a computerized image analysis system. Excellent survival (> or =95 percent) was noted in 16 of 21 arterialized venous flaps in group 1 versus 2 of 21 in group 2 (p < 0.01). Partial survival (50 to 94 percent) was observed in 2 of 21 arterialized venous flaps in group 1 and 15 of 21 in group 2. Poor survival (<50 percent) was noted in 3 of 21 in group 1 and in 4 of 21 in group 2. Microangiography was used to illustrate arteriovenous fistulas, the vascular network within the flaps, and neovessels in the periphery of the flaps. These data indicate that neovascularization is necessary for optimal survival of arterialized venous flaps in this experimental rabbit ear model.

References

Apr 1, 1992·Plastic and Reconstructive Surgery·I KoshimaM Yamasaki
Sep 1, 1991·The Journal of Trauma·H C ChenM S Noordhoff
Jan 1, 1991·British Journal of Plastic Surgery·I KoshimaJ Tanaka
Mar 1, 1990·British Journal of Plastic Surgery·G InoueK Suzuki
Jul 1, 1989·Journal of Reconstructive Microsurgery·Y InadaK Masuhara
Apr 1, 1989·Plastic and Reconstructive Surgery·E H RoseM S Norris
Nov 1, 1988·Plastic and Reconstructive Surgery·S L ChiaL Mao
Jan 1, 1986·Plastic and Reconstructive Surgery·M J Rees, G I Taylor
Jan 1, 1986·Plastic and Reconstructive Surgery·M J Timmons
Jan 1, 1985·Plastic and Reconstructive Surgery·S M BaekH F Biller
Aug 1, 1985·American Journal of Surgery·L S Nichter, P C Haines
Oct 1, 1984·Plastic and Reconstructive Surgery·S D LinC C Chiu
Jan 1, 1984·British Journal of Plastic Surgery·P L Townsend, G I Taylor
Apr 1, 1984·Archives of Otolaryngology·J C Mundy, W R Panje
Mar 1, 1981·Plastic and Reconstructive Surgery·Y NakayamaY Kasai
Jul 1, 1951·Circulation·R HEIMBECKERA BLALOCK
Feb 1, 1906·Annals of Surgery·A Carrel, C C Guthrie

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Citations

Sep 4, 1998·Microsurgery·U KantarciC Gürbüz
May 13, 2003·Microsurgery·Harald E T MoshammerHorst Koch
Apr 7, 1998·Plastic and Reconstructive Surgery·S H WooJ H Seul
Mar 2, 2012·Microsurgery·Warren M RozenJames Leong
Oct 5, 2001·British Journal of Plastic Surgery·B WungcharoenV Chongchet
Feb 24, 2001·British Journal of Plastic Surgery·B WungcharoenV Chongchet
Jun 23, 2016·Journal of Plastic, Reconstructive & Aesthetic Surgery : JPRAS·Yu-Te LinChih-Hung Lin
May 6, 2005·The International Journal of Lower Extremity Wounds·Michael SchäfferHorst-Dieter Becker
Mar 24, 2004·Microsurgery·Horst KochHarald E T Moshammer
Jul 23, 2004·Annals of Plastic Surgery·Marzia SalgarelloEugenio Farallo
Dec 4, 2008·Plastic and Reconstructive Surgery·Brigitte PittetAjay L Mahajan
Sep 6, 2005·Plastic and Reconstructive Surgery·Chi-Ho LeeWoo-Kyung Kim
Apr 19, 2007·Plastic and Reconstructive Surgery·Sang-Hyun WooKyeong Soo Lee
Oct 6, 2000·Scandinavian Journal of Plastic and Reconstructive Surgery and Hand Surgery·Y B TangH C Chen
Aug 1, 2013·Plastic and Reconstructive Surgery. Global Open·Martín IglesiasMelina Díaz-Morales
Apr 30, 2019·Plastic and Reconstructive Surgery·Diogo CasalJoão Goyri-O'Neill

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