PMID: 9420832Nov 1, 1995Paper

The role of nitrogen 13 ammonia positron emission tomography in predicting functional outcome after coronary revascularization

Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology
C S DuvernoyM Schwaiger

Abstract

We sought to evaluate the predictive value of positron emission tomography (PET) by using blood flow imaging with semiquantitative data analysis techniques for predicting recovery of regional function after revascularization. Positron emission tomography in combination with fluorodeoxyglucose (FDG) has been shown to predict tissue recovery after revascularization. Previous studies have suggested a quantitative threshold for perfusion as evaluated by PET that separates scar from viable tissue. In a group of 25 patients with impaired regional wall motion at baseline as measured by radionuclide ventriculography, we examined the relationship between myocardial blood flow and functional outcome of myocardial segments in patients who underwent coronary revascularization within 2 months after PET. Regional wall motion was graded on a 5-point scale, from normal to dyskinetic. Regional nitrogen 13 (N-13) ammonia uptake values were expressed as a percentage of maximal myocardial N-13 ammonia uptake and compared with values obtained from healthy volunteers. Results were displayed as polar maps, on which regions of interest were placed corresponding to revascularized vascular territories. We were able to show a statistically significant re...Continue Reading

References

Aug 1, 1988·The American Journal of Cardiology·D S FreedmanJ J Barboriak
Apr 3, 1986·The New England Journal of Medicine·J TillischH Schelbert
Dec 1, 1986·Journal of the American College of Cardiology·E Braunwald, J D Rutherford

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Citations

Jul 9, 2003·Annals of Nuclear Medicine·Ichiro MatsunariKinichi Hisada
Sep 23, 2014·Seminars in Nuclear Medicine·Sharmila Dorbala, Marcelo F Di Carli
Apr 4, 2002·Nuclear Medicine Communications·George Segall
Jun 28, 2018·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·Andrew Van ToshKenneth J Nichols

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