The role of ozonized oil and a combination of tobramycin/dexamethasone eye drops in the treatment of viral conjunctivitis: a randomized clinical trial.

International Ophthalmology
C CaginiA Mencacci

Abstract

To determine whether topical tobramycin 0.3%/dexamethasone 0.1% plus ozonized oil eye drops reduces clinical signs and infectious viral titers of presumed viral conjunctivitis more than tobramycin/dexamethasone eye drops alone. Prospective, single-blind, randomized, parallel-groups trial. Eighty patients with a clinical diagnosis of presumed viral conjunctivitis were randomizedly divided into two treatment groups: a study group and a control group, 40 for each group. Patients in the study group received topical tobramycin 0.3%/dexamethasone 0.1% eye drops, plus ozonized oil eye drops, both four times daily; patients in the control group received only topical tobramycin 0.3%/dexamethasone eye drops four times daily. The treatment was for seven days in both groups. Swabs were taken from the conjunctival fornix for adenovirus PCR analysis on the day of recruitment and at seven days follow-up. Clinical signs were also recorded on the day of recruitment and at follow-up examination: the main outcomes were conjunctival injection and conjunctival chemosis, graded on a 4-point clinical scale, presence or absence of superficial punctate keratitis and subepithelial corneal infiltrates. No statistically significant difference was reached ...Continue Reading

References

May 1, 1992·Transactions of the Royal Society of Tropical Medicine and Hygiene·R M WoodlandM Shah
Dec 1, 1991·Ophthalmology·M G Speaker, J A Menikoff
Jan 1, 1987·Epidemiologic Reviews·E FordD Warren
Oct 1, 1988·Ophthalmology·K J Hyde, S T Berger
Apr 1, 1981·The Journal of Pediatrics·F GigliottiJ Wood
Apr 1, 1982·Journal of Clinical Microbiology·R L BerkelmanR L Anderson
May 1, 1996·Archives of Ophthalmology·E G RomanowskiY J Gordon
Jul 1, 1997·American Journal of Ophthalmology·S J IsenbergN K Lam
Aug 31, 2001·Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift für Augenheilkunde·K KashiwagiS Tsukahara
Apr 29, 2005·Journal of Ocular Pharmacology and Therapeutics : the Official Journal of the Association for Ocular Pharmacology and Therapeutics·Barbara TeuchnerClara Larcher
Nov 26, 2005·The British Journal of Dermatology·G ValacchiV Bocci
Jul 5, 2008·Journal of Virological Methods·Byron K MurrayKim L O'Neill
Jun 13, 2009·Recent Patents on Anti-infective Drug Discovery·Valter TravagliVelio Bocci
Jun 23, 2009·Journal of Korean Medical Science·Hee Su KimYoung Min Park
Jun 26, 2009·Current Medical Research and Opinion·Terrence P O'BrienMichael B Raizman
Oct 24, 2013·JAMA : the Journal of the American Medical Association·Amir A Azari, Neal P Barney
Jun 17, 2015·Survey of Ophthalmology·Vishal JhanjiRasik B Vajpayee
Apr 18, 2018·Eye & Contact Lens·Debora Garcia-ZalisnakAndrew R Davis
Jun 22, 2018·Case Reports in Ophthalmology·Leopoldo SpadeaAndrea Marchegiani
Jul 27, 2018·Infection and Drug Resistance·DeGaulle I Chigbu, Bisant A Labib
Jul 6, 2019·Cornea·Edward J HollandFrancis S Mah

❮ Previous
Next ❯

Citations

May 22, 2021·International Medical Case Reports Journal·Fedele PassidomoCiro Costagliola
Aug 25, 2021·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Daniele TognettoGabriella Cirigliano
Nov 14, 2021·Microbial Biotechnology·Lucrezia ZerilloTiziana Zotti

❮ Previous
Next ❯

Methods Mentioned

BETA
PCR

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.