The role of p34 kinases in the G1 to S-phase transition

Cell cycle checkpoints are a series of complex checkpoint mechanisms that detect DNA abnormalities and ensure that DNA replication and repair are complete before cell division. They are primarily regulated by cyclins, cyclin-dependent kinases, and the anaphase-promoting complex/cyclosome. Here is the latest research.

Cell Cycle Pathways

Cell cycle is a complex process regulated by several signal transduction pathways and enzymes. Here is the latest research on regulation of cell cycle and cell cycle pathways.

The role of p34 kinases in the G1 to S-phase transition

Abstract

Citations

Estrogen-induced cyclin D1 and D3 gene expressions during mouse uterine cell proliferation in vivo: differential induction mechanism of cyclin D1 and D3

A qualitative and quantitative protein database approach identifies individual and groups of functionally related proteins that are differentially regulated in simian virus 40 (SV40) transformed human keratinocytes: an overview of the functional changes associated with the transformed phenotype

Control of cell cycle entry and progression in mitogen-stimulated human B lymphocytes

Cell cycle reentry of mammalian fibroblasts is accompanied by the sustained activation of p44mapk and p42mapk isoforms in the G1 phase and their inactivation at the G1/S transition

Differential regulation of the synthesis and activity of the major cyclin-dependent kinases, p34cdc2, p33cdk2, and p34cdk4, during cell cycle entry and progression in normal human T lymphocytes

Assembly and functions of the spindle pole body in budding yeast

Evasion of apoptosis by DNA viruses

Phosphorylation of Cdc28 and regulation of cell size by the protein kinase CKII in Saccharomyces cerevisiae

Mitogen-activated protein kinases p42mapk and p44mapk are required for fibroblast proliferation

Altered regulation of G1 cyclins in senescent human diploid fibroblasts: accumulation of inactive cyclin E-Cdk2 and cyclin D1-Cdk2 complexes

A cell cycle-regulated inhibitor of cyclin-dependent kinases

Exit from G0 and entry into the cell cycle of cells expressing p21Sdi1 antisense RNA

Cdc37 is required for association of the protein kinase Cdc28 with G1 and mitotic cyclins

Identification of human cyclin-dependent kinase 8, a putative protein kinase partner for cyclin C

The SLT2 (MPK1) MAP kinase homolog is involved in polarized cell growth in Saccharomyces cerevisiae

Role of Bud3p in producing the axial budding pattern of yeast

Members of the NAP/SET family of proteins interact specifically with B-type cyclins

NAP1 acts with Clb1 to perform mitotic functions and to suppress polar bud growth in budding yeast

BED1, a gene encoding a galactosyltransferase homologue, is required for polarized growth and efficient bud emergence in Saccharomyces cerevisiae

Detection of protein kinase activity specifically activated at metaphase-anaphase transition

Clinical protocol. Tumor site specific phase I evaluation of safety and efficacy of hepatic arterial infusion of a matrix-targeted retroviral vector bearing a dominant negative cyclin G1 construct as intervention for colorectal carcinoma metastatic to liver

Cell cycle-regulated degradation of Xenopus cyclin B2 requires binding to p34cdc2

Expression and activity of p40MO15, the catalytic subunit of cdk-activating kinase, during Xenopus oogenesis and embryogenesis

TOR controls translation initiation and early G1 progression in yeast

Ran1 functions to control the Cdc10/Sct1 complex through Puc1

Mcm2 and Mcm3 are constitutive nuclear proteins that exhibit distinct isoforms and bind chromatin during specific cell cycle stages of Saccharomyces cerevisiae

A conserved cell growth cycle can account for the environmental stress responses of divergent eukaryotes.

Yeast spore germination: a requirement for Ras protein activity during re-entry into the cell cycle

Nif1, a novel mitotic inhibitor in Schizosaccharomyces pombe

Regulation of the replication initiator protein p65cdc18 by CDK phosphorylation

CLB5 and CLB6 are required for premeiotic DNA replication and activation of the meiotic S/M checkpoint

The molecular mechanism of mitotic inhibition of TFIIH is mediated by phosphorylation of CDK7

An Arabidopsis cell cycle -dependent kinase-related gene, CDC2b, plays a role in regulating seedling growth in darkness

Distinct classes of cdc2-related genes are differentially expressed during the cell division cycle in plants

Distinct phospholipase C-β isozymes mediate lysophosphatidic acid receptor 1 effects on intestinal epithelial homeostasis and wound closure

Cyclin D1 amplification and expression in human breast carcinoma: correlation with histological prognostic markers and oestrogen receptor expression.

Cell polarity and morphogenesis in budding yeast

Expression of the cyclin-dependent kinase cdk4 in perinatal and adult rat lung

The cyclin D1 (CCND1) rs9344 G>A polymorphism predicts clinical outcome in colon cancer patients treated with adjuvant 5-FU-based chemotherapy.

Cyclin A activates the DNA polymerase delta -dependent elongation machinery in vitro: A parvovirus DNA replication model

Cell cycle-dependent phosphorylation of mammalian protein phosphatase 1 by cdc2 kinase

EGF receptor expression, regulation, and function in breast cancer

Cell cycle proteins and the development of oral squamous cell carcinoma

The RCK1 and RCK2 protein kinase genes from Saccharomyces cerevisiae suppress cell cycle checkpoint mutations in Schizosaccharomyces pombe

Cell cycle regulated transcription in yeast

The REC41 gene of Saccharomyces cerevisiae: isolation and genetic analysis

International Commission for Protection Against Environmental Mutagens and Carcinogens. Deoxyribonucleoside triphosphate levels: a critical factor in the maintenance of genetic stability

Apoptosis and protein expression after focal cerebral ischemia in rat

Pfcrk-1, a developmentally regulated cdc2-related protein kinase of Plasmodium falciparum

Apoptosis, cancer and the p53 tumour suppressor gene

Related Concepts

Related Feeds

Cell Checkpoints & Regulators

Cell Cycle Pathways

Related Papers

Cell cycle regulation in the yeasts Saccharomyces cerevisiae and Schizosaccharomyces pombe

Cloning of the rat cyclin-dependent kinase 4 cDNA: implication in proliferation-dependent expression in rat tissues

Control of the yeast cell cycle by the Cdc28 protein kinase

Animal cell cycles and their control

Phosphorylation of synthetic vimentin peptides by cdc2 kinase