The role of parent and offspring sex on risk for externalizing psychopathology in offspring with parental alcohol use disorder: a national Swedish study

Social Psychiatry and Psychiatric Epidemiology
Elizabeth C LongK S Kendler

Abstract

The substantial literature showing that offspring of parents with alcohol use disorder (AUD) is at increased risk for externalizing psychopathology rarely examines the differential effects of parental and offspring sex. This literature also has other important limitations, such as modest sample sizes and use of unrepresentative samples. Using a large, nationwide Swedish sample, we aim to investigate the roles of parental and offspring sex in externalizing psychopathology among offspring with parental AUD. AUD diagnosis and externalizing measures were obtained from national registries. Associations between outcomes and parental AUD were examined using logistic regressions. Parental and offspring sex effects were examined with interaction terms. Risks for externalizing disorders were increased in sons and daughters with parental AUD, with significant differences between sons and daughters for criminal behavior; maternal AUD had a greater impact than paternal AUD (regardless of offspring sex), but having two parents with AUD increased risk for all outcomes substantially more than having one parent; and maternal AUD increased risk of drug abuse for daughters more than sons, while paternal AUD increased risk of AUD and criminal beha...Continue Reading

References

Nov 1, 1991·The International Journal of the Addictions·R J Ackerman, E W Gondolf
Nov 1, 1987·The Journal of Nervous and Mental Disease·V E PollockD W Goodwin
Aug 12, 1999·Alcoholism, Clinical and Experimental Research·C A PrescottK S Kendler
Jun 30, 2001·The American Journal of Psychiatry·E KringlenV Cramer
Sep 8, 2004·Archives of General Psychiatry·Brian M HicksChristopher J Patrick
Jun 1, 2005·European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology·Jürgen RehmFrank Jacobi
Jun 9, 2005·Archives of General Psychiatry·Ronald C KesslerEllen E Walters
May 2, 2006·Journal of Abnormal Child Psychology·Ellen P EdwardsKenneth E Leonard
Oct 13, 2007·Social Psychiatry and Psychiatric Epidemiology·Rosa DíazIsabel Garbayo
Apr 22, 2009·Epidemiologia e psichiatria sociale·Ronald C KesslerPhilip S Wang
Jul 17, 2010·The American Journal of Psychiatry·Marina A BornovalovaMatt McGue
Dec 7, 2011·Journal of Korean Academy of Nursing·Hee Kyung Kim, Mi Hyoung Lee
Mar 7, 2012·Archives of General Psychiatry·Kenneth S KendlerJan Sundquist
Jul 31, 2013·Alcoholism, Clinical and Experimental Research·Kenneth S KendlerDanielle M Dick
Jan 8, 2015·JAMA Psychiatry·Kenneth S KendlerKristina Sundquist
Feb 24, 2015·Addictive Behaviors·Elise N Marino, Kim Fromme
Oct 24, 2015·Behavior Genetics·Kenneth S KendlerKristina Sundquist
Dec 6, 2016·Alcoholism, Clinical and Experimental Research·Elizabeth C LongKenneth S Kendler
Dec 10, 2016·Journal of Studies on Alcohol and Drugs·Gretchen R B SaundersIrene J Elkins

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