The role of physician characteristics in clinical trial acceptance: testing pathways of influence

Journal of Health Communication
Barbara CurbowLisa Benz Scott

Abstract

Eight videotaped vignettes were developed that assessed the effects of three physician-related experimental variables (in a 2 x 2 x 2 factorial design) on clinical trial (CT) knowledge, video knowledge, information processing, CT beliefs, affective evaluations (attitudes), and CT acceptance. It was hypothesized that the physician variables (community versus academic-based affiliation, enthusiastic versus neutral presentation of the trial, and new versus previous relationship with the patient) would serve as communication cues that would interrupt message processing, leading to lower knowledge gain but more positive beliefs, attitudes, and CT acceptance. A total of 262 women (161 survivors and 101 controls) participated in the study. The manipulated variables primarily influenced the intermediary variables of post-test CT beliefs and satisfaction with information rather than knowledge or information processing. Multiple regression results indicated that CT acceptance was associated with positive post-CT beliefs, a lower level of information processing, satisfaction with information, and control status. Based on these results, CT acceptance does not appear to be based on a rational decision-making model; this has implications for...Continue Reading

References

Nov 1, 1991·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·A B BensonK Anderson
Jan 1, 1991·Preventive Medicine·H LeventhalL M Bendena
Jan 1, 1991·Medical and Pediatric Oncology·W B FisherP J Loehrer
Apr 17, 1980·The New England Journal of Medicine·T M Grundner
May 1, 1995·Patient Education and Counseling·H A Llewellyn-ThomasD E Woermke
Mar 1, 1993·Italian Journal of Neurological Sciences·G RistoriC Fieschi
Aug 15, 1994·Cancer·G R Morrow, A J Bellg
Mar 1, 1996·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·N K AaronsonR Dubbelman
Apr 1, 1996·Journal of Community Health·S B RobinsonM A Haynes
Sep 23, 1998·Australian and New Zealand Journal of Public Health·P M Ellis, P N Butow
May 1, 1999·Seminars in Oncology Nursing·H A Taylor
Oct 3, 1999·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·T L AlbrechtR Strongbow
Mar 10, 2001·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·C A Sawka, K I Pritchard
Aug 2, 2001·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·P M EllisN Houssami
Mar 22, 2002·Journal of Internal Medicine·S M MadsenP Riis
Aug 28, 2002·Annals of Oncology : Official Journal of the European Society for Medical Oncology·P M EllisM H N Tattersall
Aug 31, 2002·Psycho-oncology·M J HenmanM H N Tattersall
Feb 21, 2003·The New England Journal of Medicine·Michael K Paasche-OrlowFrederick L Brancati
Oct 24, 2003·Social Science & Medicine·Barbara CurbowLisa Benz Scott

❮ Previous
Next ❯

Citations

Dec 17, 2009·Prevention Science : the Official Journal of the Society for Prevention Research·Paula M FrewCarlos del Rio
Jun 6, 2009·Health Communication·Scott D MooreDaniel R Bernard
Aug 3, 2010·Health Communication·Z Janet YangHildy Dillon
Jan 11, 2011·Health Communication·Jon D MillerLinda G Kimmel
Dec 4, 2010·Journal of Health Communication·Janice L KriegerJon F Nussbaum
Apr 15, 2010·Journal of Health Communication·Katherine A McComasHildy Dillon
Sep 13, 2006·Health Communication·William Evans
Mar 23, 2010·Journal of Clinical Epidemiology·Paula M FrewCarlos del Rio
Jun 21, 2016·Human Vaccines & Immunotherapeutics·Paula M FrewSaad B Omer

❮ Previous
Next ❯

Methods Mentioned

BETA
dissection

Software Mentioned

AMOS
Analysis of Moment Structures ( AMOS )

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology
Robert L ComisEllen Stoval
JAMA : the Journal of the American Medical Association
Vivek H MurthyCary P Gross
© 2021 Meta ULC. All rights reserved