The Role of Platelet Concentrates in Facial Fat Grafting

Annals of Plastic Surgery
Shaoheng XiongChenggang Yi

Abstract

Autologous fat grafting is increasingly being used as a method for the repair of facial soft tissue defects and facial rejuvenation, given its low risk of adverse effects and high efficacy. However, the unpredictability of graft retention is a limitation of this procedure. In addition, there is no standard procedure to date for autologous fat grafting. Different methods have been developed to increase the retention of grafted fat. For instance, platelet concentrates have been used to directly deliver bioactive factors to grafted fat. Platelet concentrates also provide incidental therapeutic benefits by enhancing the persistence of fat grafted in the face via the release of growth factors and cytokines. In this review, we describe current strategies for improving the survival of facial fat grafts, mainly focusing on the application of growth factors/cytokines and platelet concentrates to fat grafting.

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Citations

May 29, 2019·Plastic and Reconstructive Surgery·Shaoheng XiongChenggang Yi
Mar 19, 2020·Aesthetic Plastic Surgery·Jianguo ChenHaiyue Jiang
Nov 20, 2019·Clinics in Plastic Surgery·Shaoheng XiongLee L Q Pu
Jun 10, 2021·Experimental Biology and Medicine·J Sarah CrowleyMarek Dobke

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