PMID: 2506160Sep 1, 1989Paper

The role of post-operative radiation in the prevention of heterotopic ossification in patients with post-traumatic acetabular fracture

International Journal of Radiation Oncology, Biology, Physics
R G SlawsonA R Burgess

Abstract

Heterotopic ossification (HO) with subsequent pain and limitation of motion of the lower extremity is a common and significant problem for patients who suffer traumatic acetabular fracture (TAF). The incidence of heterotopic ossification is markedly increased for patients requiring surgical repair depending on the degree of trauma and the type of surgical repair necessary. Radiation therapy (RT) has proven to be the most effective surgical adjunct for the prevention of heterotopic ossification in patients undergoing total hip replacement (THR), but has not been reported in patients with traumatic fracture and repair. This report details an experience with patients treated at a Shock Trauma Center with extensile repair and immediate (within 48 hr) post-operative radiation therapy given as 5 daily fractions of 2 Gy in 5 to 7 days to a total dose of 10 Gy using megavoltage radiation therapy. A total of 30 consecutive patients (RT group) have been treated at our institution since June 1985. The last 20 patients treated with surgery only (non-RT group) prior to initiation of this study were used as a control group. Heterotopic ossification was seen to some degree in 50% of all radiation therapy patients, but was severe in only three...Continue Reading

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Citations

Jun 19, 2008·Clinical & Translational Oncology : Official Publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico·A Montero LuisA Ramos Aguerri
Nov 8, 2001·International Journal of Radiation Oncology, Biology, Physics·M H SeegenschmiedtUNKNOWN German Cooperative Group on Radiotherapy for Benign Diseases
Nov 20, 2002·ANZ Journal of Surgery·Bruce NealLouisa Dunn
Sep 16, 1999·International Journal of Radiation Oncology, Biology, Physics·M L HaasR G Slawson
May 31, 2002·The British Journal of Radiology·P G S CornesJ P Glees
Nov 15, 1993·International Journal of Radiation Oncology, Biology, Physics·E D DurrR L Foote
May 1, 1997·Journal of Shoulder and Elbow Surgery·S L SummerfieldA P Weiss
Sep 16, 2014·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Marko PopovicEdward Chow
Oct 27, 2015·Clinical Orthopaedics and Related Research·Jason A DavisJoshua L Gary
Sep 5, 1998·Clinical Orthopaedics and Related Research·J P Stannard, J E Alonso
Jun 13, 2003·ANZ Journal of Surgery·Bruce Neal
Mar 27, 1999·Seminars in Radiation Oncology·T C Lo
Dec 3, 2021·Archives of Orthopaedic and Trauma Surgery·Ramakanth R YakkantiStephen M Quinnan
Aug 30, 1994·International Journal of Radiation Oncology, Biology, Physics·M H SeegenschmiedtR Sauer

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