The role of pre-existing comorbidity on the rate of recovery following injury: A longitudinal cohort study

PloS One
Gabrielle DavieSarah Derrett

Abstract

Understanding the role of comorbidity in recovery following injury is an important challenge given the increasing prevalence of multimorbidity (2 or more comorbidities) in many countries. The Prospective Outcomes of Injury Study recruited 2856 injured 18-64 year olds that had registered for entitlements with New Zealand's universal no-fault injury insurer. Recovery, or lack of, in this longitudinal cohort was measured using the World Health Organization Disability Assessment Schedule at 3, 12 and 24 months post-injury. Twenty-one pre-existing chronic conditions were used to identify comorbidity. To investigate whether rates of recovery differed by pre-injury comorbidity, the interaction between time and comorbidity was modelled using Generalised Estimating Equations. Of 1,862 participants with complete data, the distribution reporting none, one comorbidity, or multimorbidity pre-injury was 51%, 27%, and 21% respectively. Longitudinal analysis estimated no difference (log odds per year 0.05, 95% Confidence Interval -0.17 to 0.27) between the rate of change of disability for those with one pre-injury comorbidity compared to those with none. Those with pre-injury multimorbidity had significantly slower reduction in disability over...Continue Reading

References

Apr 6, 2001·Injury Prevention : Journal of the International Society for Child and Adolescent Injury Prevention·M StevensonG McDonald-Smith
Jan 12, 2007·The Journal of Trauma·Suzanne PolinderWillem Jan Meerding
Jul 15, 2009·Annals of Family Medicine·Jose M ValderasMartin Roland
Oct 13, 2009·The Journal of Trauma·Sarah DerrettG Peter Herbison
Dec 18, 2009·Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation·Juan V LucianoJosep M Haro
Dec 19, 2009·PloS One·Gavin AndrewsTevik Bedirhan Ustun
Jul 5, 2011·Injury Prevention : Journal of the International Society for Child and Adolescent Injury Prevention·Sarah DerrettJohn Langley
Jan 29, 2013·BMC Health Services Research·Belinda J GabbeUNKNOWN Victorian Orthopaedic Trauma Outcomes Registry
Mar 19, 2013·Injury Prevention : Journal of the International Society for Child and Adolescent Injury Prevention·John Desmond LangleyBrendan Hokowhitu
Dec 5, 2015·Injury Prevention : Journal of the International Society for Child and Adolescent Injury Prevention·Juanita A HaagsmaTheo Vos
Dec 31, 2015·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·Richard A GoodmanBruce S Finke
Jan 19, 2016·Annals of Surgery·Belinda J GabbePeter A Cameron
Nov 2, 2017·Journal of Comorbidity·Maartje J van der AaThomas Plochg

❮ Previous
Next ❯

Citations

Nov 20, 2019·Journal of Occupational and Environmental Medicine·Shannon E Gray, Alex Collie
Apr 21, 2019·Injury Prevention : Journal of the International Society for Child and Adolescent Injury Prevention·Stella SamoborecSue Evans
May 31, 2020·Health and Quality of Life Outcomes·A J L M GeraerdsSuzanne Polinder
Aug 17, 2020·Occupational and Environmental Medicine·Helen HarcombeSarah Derrett
Jul 10, 2019·Australian and New Zealand Journal of Public Health·Warinthon BakerSarah Derrett
Oct 8, 2020·Australasian Journal on Ageing·Katherine BrownRebecca Ivers
Jun 3, 2021·Methods and Protocols·Sarah DerrettHelen Harcombe
Jun 3, 2021·Methods and Protocols·Emma H WyethHelen Harcombe
Sep 21, 2021·BMC Health Services Research·Marjolein van der VlegelJuanita A Haagsma

❮ Previous
Next ❯

Software Mentioned

Polinder

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Australian and New Zealand Journal of Public Health
Emma WyethSarah Derrett
Injury Prevention : Journal of the International Society for Child and Adolescent Injury Prevention
Sarah DerrettJohn Langley
Injury Prevention : Journal of the International Society for Child and Adolescent Injury Prevention
Helen HarcombeSarah Derrett
Injury Prevention : Journal of the International Society for Child and Adolescent Injury Prevention
Sarah DerrettDave Barson
© 2022 Meta ULC. All rights reserved