PMID: 11906584Mar 22, 2002Paper

The role of probiotics and prebiotics in the management of diarrhoea associated with enteral tube feeding

Journal of Human Nutrition and Dietetics : the Official Journal of the British Dietetic Association
Kevin WhelanM A Taylor

Abstract

Diarrhoea is a common and serious complication of enteral tube feeding, and has a range of aetiologies. Manipulation of the colonic microflora may reduce the incidence of enteral tube feeding diarrhoea via suppression of enteropathogens and production of short-chain fatty acids. Probiotics and prebiotics are commonly used during enteral tube feeding to manipulate the colonic microflora; however, their efficacy is as yet uncertain. English-language studies investigating the pathogenesis of enteral tube feeding diarrhoea and the use of probiotics and prebiotics were identified by searching the electronic databases CINAHL, EMBASE and MEDLINE from 1980 to 2001. The bibliographies of articles obtained were searched manually. Only two prospective, randomized, double-blind, placebo-controlled trials have investigated the effect of a probiotic on enteral tube feeding diarrhoea; however, results are conflicting. No prospective, randomized, double-blind, placebo-controlled studies have specifically addressed the effect of a prebiotic on the incidence of enteral tube feeding diarrhoea. Theoretically, probiotics and prebiotics may be of benefit in prophylaxis against enteral tube feeding diarrhoea; however, there is currently insufficient ...Continue Reading

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Citations

Sep 26, 2002·Nutrition·Kevin WhelanMoira A Taylor
Apr 22, 2004·The Proceedings of the Nutrition Society·Kevin WhelanMoira A Taylor
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