The Role of Probiotics in Colorectal Cancer Management

Evidence-based Complementary and Alternative Medicine : ECAM
Bhagavathi Sundaram SivamaruthiChaiyavat Chaiyasut

Abstract

Colorectal cancer (CRC) is one of the most common cancerous diseases worldwide and causes leading cancer-associated deaths. Several factors are related to the incidence of CRC such as unhealthy diet and lifestyle, heredity, metabolic disorders, and genetic factors. Even though several advanced medical procedures are available for CRC treatment, the survival rates are poor with many adverse treatments associated side effects, which affects the quality of life. Probiotics are a well-known bioactive candidate for the treatment of several diseases and ill-health conditions. The recent scientific evidence suggested that probiotic supplementation protects the CRC patients from treatment-associated adverse effects. The manuscript summarizes the influence of probiotic supplementation on the health status of CRC patients and discusses the possible mechanism behind the protective effect of probiotics against CRC. The literature survey revealed that beneficial impact of probiotic supplementation depends on several factors such as strain, dosage, duration of the intervention, host physiology, and other food supplements. The probiotic intervention improves the microbiota, releases antimicrobials and anticarcinogenic agents, helps to remove ...Continue Reading

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Citations

May 10, 2020·Cancers·Purushottam LamichhaneRahul R Deshmukh
Jan 6, 2021·Biotechnology and Applied Biochemistry·Samreen AhsanMuthu Thiruvengadam
Dec 4, 2020·World Journal of Gastroenterology : WJG·Denise Sayuri Calheiros SilveiraGabriela Pereira-da-Silva
Apr 29, 2021·Drug Design, Development and Therapy·Xiao-Chong LiZhi-Qiang Li
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May 4, 2021·Journal of Dairy Science·Celso F BalthazarMarzia Albenzio
Jul 31, 2021·Frontiers in Oncology·Siying WangZhaoxia Wang
Aug 25, 2021·Journal of Industrial Microbiology & Biotechnology·Alejandra Mejía CaballeroAmelia Farrés
Nov 9, 2021·Clinical & Experimental Metastasis·Charlotte HenstraAnika Nagelkerke

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Methods Mentioned

BETA
biopsy
biopsies

Software Mentioned

Scopus
Google Scholar
ResearchGate
LactoLevure
PubMed

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