The role of radical gastrectomy with systematic lymphadenectomy for the diagnosis and treatment of primary gastric lymphoma

Annals of Surgery
Y KoderaT Kito

Abstract

We evaluated the therapeutic efficacy of radical gastrectomy for primary B-cell lymphoma of the stomach and attempted to identify patients who could be adequately treated with surgery alone. Several recent gastric lymphoma reports have discussed the therapeutic benefits of various treatment strategies for stage IE and IIE lymphoma. However, few studies have been based on patients accurately staged by systematic lymphadenectomy with subsequent pathologic examination. A retrospective study was performed to evaluate the survival and biologic behavior of lesions in 60 patients with gastric lymphoma who were treated by radical gastrectomy alone. Tumors were classified according to the histopathologic concept of mucosa-associated lymphoid tissue (MALT)-derived lymphoma. A low histopathologic grade was associated with a significantly lower incidence of nodal metastasis (p = 0.07) and less extensive infiltration of the gastric wall (p < 0.005) despite larger tumor size. A 5-year survival rate of >95% was attained with surgery alone for MALT lymphoma and for true stage IE lymphoma diagnosed by pathologic examination of up to N2 lymph nodes routinely performed after radical gastrectomy. Surgery alone is adequate treatment for stage IE or...Continue Reading

References

Feb 1, 1990·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·M H MaorK B Silvermintz
Jan 1, 1991·Scandinavian Journal of Gastroenterology. Supplement·B G Taal, J M Burgers
Nov 1, 1991·Gastroenterology·S B CogliattiK Lennert
May 1, 1991·American Journal of Surgery·V L RacknerJ A Ryan
Aug 1, 1990·Archives of Surgery·M S TalamontiD L Nahrwold
Feb 1, 1988·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·F A ShepherdM A Baker
Apr 21, 1988·The New England Journal of Medicine·J Pedersen-BjergaardM M Hansen
Jun 1, 1987·The British Journal of Surgery·M S HockeyJ W Fielding
Apr 1, 1985·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·W P SheridanG N Brodie
Oct 1, 1995·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·P HammelJ C Delchier
Jan 1, 1995·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·A M BuntJ A Bruijn
Feb 1, 1994·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·A M BuntJ A Bruijn
Jun 1, 1994·Cancer·M ShimodairaT Nagasaka
May 1, 1993·American Journal of Surgery·R J SchwarzN Schmidt

❮ Previous
Next ❯

Citations

Nov 30, 2000·Current Treatment Options in Gastroenterology·R G Sheehan
Mar 13, 1999·Seminars in Oncology Nursing·K G O'Connor
Jun 24, 2004·Annals of Surgery·Sam S YoonMartin S Karpeh
Jun 5, 2007·Annals of Surgical Oncology·Heriberto Medina-FrancoCarmen Lome Maldonado
Apr 18, 2002·AJR. American Journal of Roentgenology·Dongil ChoiYoung Hyeh Ko
Nov 9, 2011·World Journal of Surgical Oncology·Roberto CirocchiCarlo Boselli
Jun 30, 2004·Leukemia & Lymphoma·Wolf-Peter SchmidtRuth Sonnen
Oct 23, 2008·The Surgeon : Journal of the Royal Colleges of Surgeons of Edinburgh and Ireland·P BalfeJ V Reynolds
Apr 29, 2009·Journal of Surgical Oncology·Michael C CheungLeonidas G Koniaris
Feb 24, 2007·Internal Medicine Journal·M-L LinJ F Seymour
Dec 25, 2013·The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi·Seung Soo Lee, In Ho Kim
Dec 27, 2003·World Journal of Gastroenterology : WJG·Ahmad M Al-AkwaaIbrahim A Al-Mofleh
Apr 8, 2004·World Journal of Gastroenterology : WJG·Seong-Ho KongKuk-Jin Choe
Jun 15, 2006·World Journal of Gastroenterology : WJG·Erhan HamalogluAhmet Ozenc

❮ Previous
Next ❯

Related Concepts

Related Feeds

B-Cell Lymphoma

B-cell lymphomas include lymphomas that affect B cells. This subtype of cancer accounts for over 80% of non-Hodgkin lymphomas in the US. Here is the latest research.