The role of reactive oxygen species and oxidative stress in environmental carcinogenesis and biomarker development

Chemico-biological Interactions
Dominique ZiechMihalis I Panayiotidis

Abstract

Although we have greatly benefited from the use of traditional epidemiological approaches in linking environmental exposure to human disease, we are still lacking knowledge in to how such exposure participates in disease development. However, molecular epidemiological studies have provided us with evidence linking oxidative stress with the pathogenesis of human disease and in particular carcinogenesis. To this end, oxidative stress-based biomarkers have proved to be essential in revealing how oxidative stress may be mediating toxicity induced by many known carcinogenic environmental agents. Therefore, throughout this review article, we aim to address the current state of oxidative stress-based biomarker development with major emphasis pertaining to biomarkers of DNA, lipid and protein oxidation.

References

Feb 26, 2000·Carcinogenesis·L J Marnett
Oct 18, 2000·Free Radical Biology & Medicine·J ChandraS Orrenius
Aug 9, 2001·BioEssays : News and Reviews in Molecular, Cellular and Developmental Biology·G L DianovD T Goodhead
Jan 25, 2003·Journal of Biochemistry and Molecular Biology·Roger W L GodschalkHelmut Bartsch
Feb 19, 2003·Clinica Chimica Acta; International Journal of Clinical Chemistry·Isabella Dalle-DonneRoberto Colombo
Jul 2, 2003·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·Marcus S CookeJoseph Lunec
Aug 19, 2003·Archives of Biochemistry and Biophysics·Hiroshi OhshimaTomohiro Sawa
Mar 20, 2004·Occupational and Environmental Medicine·G Castaño-VinyalsM Kogevinas
May 5, 2004·Mutagenesis·Rinne De Bont, Nik van Larebeke
May 12, 2004·Current Medicinal Chemistry·Earl R Stadtman
Sep 3, 2004·Mutation Research·Mark D EvansMarcus S Cooke
Oct 19, 2004·Seminars in Cancer Biology·Gerald N WoganLawrence A Loeb
Oct 21, 2004·Nucleic Acids Research·Alexandros G GeorgakilasBetsy M Sutherland
Mar 15, 2005·Biomarkers : Biochemical Indicators of Exposure, Response, and Susceptibility to Chemicals·William P Watson, Antonio Mutti
Jun 25, 2005·Chemistry & Biology·Erin G PrestwichShana O Kelley
Aug 27, 2005·Carcinogenesis·Paolo Vineis, Kirsti Husgafvel-Pursiainen
Dec 3, 2005·Toxicology Letters·Soterios A Kyrtopoulos
Jan 25, 2006·Chemico-biological Interactions·M ValkoM Mazur
Oct 13, 2007·Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology·Paolo Vineis, Frederica Perera
Nov 2, 2007·Radiation Research·Stewart M Holt, Alexandros G Georgakilas
Nov 17, 2007·Free Radical Biology & Medicine·Dave C FranciscoAlexandros G Georgakilas
Dec 29, 2007·Chemical Research in Toxicology·James A SwenbergRichard J Albertini
Feb 21, 2008·The Journal of Biological Chemistry·Ginger L MilneJason D Morrow
Mar 28, 2008·Cancer Letters·Peter MøllerSteffen Loft
Mar 29, 2008·Cancer Letters·Rodrigo FrancoMihalis I Panayiotidis
Apr 1, 2008·Cancer Letters·Dimitrios GalarisAlexandra Barbouti
Apr 15, 2008·Cancer Letters·Masuko Ushio-Fukai, Yoshimasa Nakamura
Jun 5, 2008·Environmental Health : a Global Access Science Source·Sam De CosterNik van Larebeke
Jun 13, 2008·Toxicology and Applied Pharmacology·Witold M Winnik, Kirk T Kitchin
Aug 12, 2008·Free Radical Biology & Medicine·Miral DizdarogluPawel Jaruga
Nov 4, 2008·Mutation Research·Salvador MenaJosé M Estrela
Jan 8, 2009·Toxicological Sciences : an Official Journal of the Society of Toxicology·Peter G WellsAndrea W Wong

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Citations

May 11, 2012·Journal of Toxicology and Environmental Health. Part B, Critical Reviews·Joachim D Pleil
Nov 28, 2012·Journal of Inflammation·Thais Helena GasparotoAna Paula Campanelli
Sep 12, 2013·SpringerPlus·Sandra Ríos-ArrabalMaria Isabel Núñez
Apr 16, 2013·International Journal of Environmental Research and Public Health·Francesca FaitaMaria Grazia Andreassi
Sep 15, 2011·World Journal of Biological Chemistry·Alexandros Georgakilas
Aug 7, 2014·Experimental and Toxicologic Pathology : Official Journal of the Gesellschaft Für Toxikologische Pathologie·Nuno Paula SantosPaula Alexandra Oliveira
Dec 17, 2011·Journal of Tropical Medicine·Michael R Peterson, Noel Weidner
Oct 23, 2013·African Journal of Traditional, Complementary, and Alternative Medicines : AJTCAM·Sarawoot Palipoch
Jun 20, 2014·Biology·Franka J Rang, Johannes Boonstra
Aug 13, 2015·Environmental Toxicology and Chemistry·Ye YangJing Liu
Dec 27, 2011·Pharmacology & Therapeutics·K AzizA G Georgakilas
Jul 26, 2011·Mutation Research·Franziska EbertTanja Schwerdtle
Jan 11, 2011·Experimental and Toxicologic Pathology : Official Journal of the Gesellschaft Für Toxikologische Pathologie·Riadh BadraouiTarek Rebai
Aug 25, 2015·Comparative Biochemistry and Physiology. Toxicology & Pharmacology : CBP·Gisela L PolettaMarta D Mudry
Jul 13, 2012·Nutrition·Vanessa Fuchs-Tarlovsky
Aug 14, 2012·Luminescence : the Journal of Biological and Chemical Luminescence·Aleksandra KładnaHassan Y Aboul-Enein
Aug 31, 2011·Journal of Toxicology·Zacharias E Suntres
Apr 2, 2016·Nucleic Acids Research·Taejin KimTamar Schlick
Apr 12, 2016·Plant Physiology and Biochemistry : PPB·Laurent UrbanJawad Aarrouf
Aug 26, 2014·Pesticide Biochemistry and Physiology·Yuanxiang JinZhengwei Fu
Mar 23, 2011·Mutation Research·Dominique ZiechMihalis I Panayiotidis
Apr 8, 2016·The Journal of Physical Chemistry. a·Mandy C GreenLyudmila V Slipchenko
Nov 29, 2011·Cancer Letters·Somaira NowsheenAlexandros G Georgakilas
Jun 28, 2011·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·Serena BenedettiFranco Canestrari
Jan 11, 2011·Mutation Research·Thomas B KrystonAlexandros G Georgakilas
Oct 4, 2011·Chemistry and Physics of Lipids·Beate FuchsJürgen Schiller
Mar 15, 2015·Journal of Environmental Sciences (China)·Xiaofei WangAn Xu
May 1, 2012·Oncology Nursing Forum·Marilyn J Hammer, Joachim G Voss
May 18, 2016·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Vadanasundari VedarethinamYoung Ock Kim
Nov 12, 2013·Toxicology and Industrial Health·Hasan Türkez, Elanur Aydın

❮ Previous
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