The role of respiratory muscles in the hyperinflation of bronchial asthma
To examine the mechanism of hyperinflation in bronchial asthma we studied lung and chest wall mechanics in 7 asymptomatic patients in whom progressive bronchoconstriction was induced by doubling the amount of inhaled aerosolized histamine. An increase in pulmonary resistance (RL) from 2.5 +/- 0.3 cmH2O . 1-1 . s (mean, +/- 1 SE) to 12.3 +/- 0.9 cmH2 was associated with a linear increase in functional residual capacity (FRC) up to 74.7 +/- 1.7% of control total lung capacity (TLCc). The mean regression coefficient was 2.3% TLCc . cmH2O-1 . 1 . s-1. At each level of hyperinflation the most positive expiratory pleural pressures measured during spontaneous breathing were generally less than the predicted chest wall relaxation pressures, indicating persistent inspiratory muscle contraction throughout expiration. This was predominantly due to inspiratory intercostal and accessory muscle activity, because measurements of transdiaphragmatic pressure indicated complete diaphragmatic relaxation early in expiration. Recruitment of abdominal muscles during expiration, inferred from measurements of gastric pressure (Pg) and abdominal antero-posterior (A-P) diameter, was progressively more apparent with increasing bronchoconstriction. We con...Continue Reading
Variation in maximum inspiratory and expiratory pressure after application of inspiratory loads in patients with COPD
Histamine challenge test in children using forced oscillation to measure total respiratory resistance
A pilot prospective, randomized, placebo-controlled trial of bilevel positive airway pressure in acute asthmatic attack
Effectiveness of therapeutic education and respiratory rehabilitation programs for the patient with asthma
Changes in respiratory and peripheral muscle function in asthmatic children: effects of inhaled corticoids
Bronchial asthma in adults: presentation to the emergency department. Part I: Pathogenesis, clinical manifestations, diagnostic evaluation, and differential diagnosis
Comparative improvement of asthma symptoms and expiratory flows after corticosteroid treatment: a method to assess the effect of corticosteroids on large vs. small airways?
Dyspnoea in health and obstructive pulmonary disease : the role of respiratory muscle function and training
Energetic cost of breathing, body composition, and pulmonary function in horses with recurrent airway obstruction
The effectiveness of combining inspiratory muscle training with manual therapy and a therapeutic exercise program on maximum inspiratory pressure in adults with asthma: a randomized clinical trial
Inspiratory muscle strength and endurance during hyperinflation and histamine induced bronchoconstriction
Analysis of tidal expiratory flow pattern in the assessment of histamine-induced bronchoconstriction
Mechanisms, measurement and management of exertional dyspnoea in asthma: Number 5 in the Series "Exertional dyspnoea" Edited by Pierantonio Laveneziana and Piergiuseppe Agostoni
Bronchodilation response to deep inspirations in asthma is dependent on airway distensibility and air trapping
Contribution of expiratory muscle pressure to dynamic intrinsic positive end-expiratory pressure: validation using the Campbell diagram
Does Bilevel Noninvasive Ventilation Have a Bronchodilating Effect and Alter Respiratory Mechanics in Asthmatic Individuals After Bronchoprovocation? Randomized, Crossover Study.
End-expiratory lung volume during arm and leg exercise in normal subjects and patients with cystic fibrosis
Elevation in lung volume and preventing catastrophic airway closure in asthmatics during bronchoconstriction
Respiratory sensation and ventilatory mechanics during induced bronchoconstriction in spontaneously breathing low cervical quadriplegia
This feed focuses in Asthma in which your airways narrow and swell. This can make breathing difficult and trigger coughing, wheezing and shortness of breath.
Allergy and Asthma
Allergy and asthma are inflammatory disorders that are triggered by the activation of an allergen-specific regulatory t cell. These t cells become activated when allergens are recognized by allergen-presenting cells. Here is the latest research on allergy and asthma.