The role of robotic gait training and tDCS in Friedrich ataxia rehabilitation: A case report

Medicine
Simona PortaroRocco Salvatore Calabrò

Abstract

Friedrich ataxia (FA) is the most common inherited neurodegenerative cerebellar ataxic syndrome. In patients with FA, physiotherapy is highly recommended to improve motor function outcome. Cerebellar transcranial direct current stimulation (tDCS) has been demonstrated to be effective in improving symptoms by modulating cerebellar excitability. Recently, robotic rehabilitation with Lokomat-Pro has been used to treat motor impairment in ataxic syndromes by "modulating" cortical plasticity and cerebello-motor connectivity. A 29-year-old Italian male with FA, come to our Institute to undergo intensive rehabilitation training. He presented a moderate-to-severe spastic tetraparesis, brisk deep tendon reflexes, moderate dysarthria, occasional difficulty in speaking, and mild delay in swallowing. He was able to stand for at least 10 seconds in the natural position with constant support, and thus he used a wheelchair. Tetraparesis in a young patient with FA. The effects of a stand-alone robotic gait training with Lokomat-Pro preceded by cerebellar anodal tDCS (a-tDCS) versus Lokomat-Pro preceded by cathodal-tDCS (c-tDCS) are compared. The coupled approach (i.e., tDCS and Lokomat) demonstrated better improvement in functional motor outco...Continue Reading

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Citations

Apr 2, 2020·The International Journal of Neuroscience·Graziella OrrùAngelo Gemignani
Dec 9, 2020·Disability and Rehabilitation. Assistive Technology·Loredana RacitiRocco Salvatore Calabrò
Mar 25, 2021·Neurological Sciences : Official Journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology·Luana Billeri, Antonino Naro
Jul 9, 2021·Journal of Multidisciplinary Healthcare·David R LynchKimberly Y Lin

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Ataxias

Ataxia is a neurological condition characterized by lack of voluntary coordination of muscle movements including loss of coordination, balance, and speech. Discover the latest research on different types of ataxias here.