The role of sentinel node biopsy in ductal carcinoma in situ of the breast

European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology
K PolomP Murawa

Abstract

Sentinel node biopsy (SNB) is an accepted alternative to lymphadenectomy in the case of invasive breast carcinoma, although the sentinel node's role in ductal carcinoma in situ (DCIS) diagnosed on core needle biopsy has not been well defined nevertheless guidelines recommend this procedure. The purpose of this study was to determine the diagnostic value of sentinel nodes in female patients with primary DCIS using core needle stereotactic biopsy. Between the years 2000 and 2005, 261 patients were diagnosed with DCIS by core needle biopsy. In this group, 183 patients underwent SNB to determine lymph node involvement. Those patients with metastases to the sentinel node underwent axillary lymphadenectomy. In the group of 183 patients that underwent SNB, 10 patients (5.5%) showed metastases to the sentinel lymph node. Histopathological studies of the primary lesions of these 10 patients revealed invasive ductal carcinoma in 6 cases (3.5%) and 1 case (0.5%) of invasive lobular carcinoma. Only 3 of the patients (1.5%) were given a final diagnosis of DCIS with metastases to sentinel lymph nodes, of which 2 cases were DCIS and 1 case was DCIS with microinvasion. Axillary lymphadenectomy performed on patients with abnormal SNB showed inv...Continue Reading

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Citations

Jan 22, 2010·World Journal of Surgical Oncology·Alessandra MascaroLucio Fortunato
Jan 29, 2010·World Journal of Surgical Oncology·Keiichiro TadaTakuji Iwase
Jun 6, 2012·ISRN Surgery·D E BolerC Uras
Jun 25, 2013·Clinical Breast Cancer·Umashankar K Ballehaninna, Ronald S Chamberlain
Jul 12, 2011·American Journal of Surgery·Tomohiro MiyakeShinzaburo Noguchi
Dec 17, 2009·Journal of Surgical Education·Ahmed Salem
Jan 1, 2012·Reports of Practical Oncology and Radiotherapy : Journal of Greatpoland Cancer Center in Poznań and Polish Society of Radiation Oncology·Karol PolomPaweł Murawa
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Apr 20, 2011·The Tohoku Journal of Experimental Medicine·Yu TangMasakazu Toi
Feb 27, 2021·Journal of breast cancer·Young Duck ShinYoung Jin Choi

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