PMID: 15220689Jun 29, 2004Paper

The role of serum zinc and other factors on the prevalence of muscle cramps in non-alcoholic cirrhotic patients

Journal of Clinical Gastroenterology
Mevlut BaskolMehmet Yucesoy

Abstract

To determine the prevalence of muscle cramps in patients with liver cirrhosis and to identify factors associated with their development, especially serum zinc. One hundred cirrhotic patients and 85 healthy subjects were enrolled into the study. True muscle cramp was defined as at least 1 painful leg cramp either occurring at rest or strong enough to waken a patient from sleep, occurring at least once a week persisting for a period of greater than 1 year. Creatinine, calcium, magnesium, sodium, potassium, zinc, glucose, alanine aminotransferase, total bilirubin, and albumin levels were detected in sera. Prothrombine time was measured in cirrhotic patients. Presence or absence of ascite was determined by sonography. True muscle cramps were significantly more common in patients with cirrhosis when compared with the control group (59% vs. 7.1%, respectively, P < 0.001). Cramp (+) cirrhotic patients had older age (49.54 +/- 10.09 vs. 55.54 +/- 7.90, respectively; p: 0.001) and higher Child-Pugh scores (7.56 +/- 2.32 vs. 9.02 +/- 2.55, respectively; p: 0.004) when compared with cramp (-) patients. None of the serum related factors such as creatinine, calcium, magnesium, sodium, potassium, zinc, glucose, alanine aminotransferase, tota...Continue Reading

References

Nov 1, 1991·Seminars in Liver Disease·C J McClainB Bacon
Mar 1, 1991·Muscle & Nerve·T S Puniani, T E Bertorini
Sep 1, 1991·Seminars in Neurology·A C Simchak, R M Pascuzzi
Dec 1, 1986·Journal of Clinical Gastroenterology·F Konikoff, E Theodor
Nov 1, 1974·Southern Medical Journal·S Ayres, R Mihan
May 1, 1983·Age and Ageing·K Jones, C M Castleden
Apr 1, 1994·Journal of the Neurological Sciences·P H JansenH Straatman
Feb 1, 1996·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·P AngeliA Gatta
Dec 8, 2000·Canadian Journal of Gastroenterology = Journal Canadien De Gastroenterologie·P J MarottaC N Ghent
Dec 14, 2002·Hepatology Research : the Official Journal of the Japan Society of Hepatology·Yasushi MatsuzakiNaomi Tanaka

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Citations

Apr 9, 2005·Journal of Clinical Gastroenterology·A D Tsakok
Jan 31, 2014·Gastroenterology Nursing : the Official Journal of the Society of Gastroenterology Nurses and Associates·Li-Hung TsaiLai-Chu See
Apr 7, 2007·Digestive Diseases and Sciences·Ioannis StamoulisStamatios Theocharis
Apr 2, 2013·Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association·Shivang S Mehta, Michael B Fallon
Jul 28, 2012·The American Journal of Medicine·Hemant ChatrathRaj Vuppalanchi
Mar 25, 2008·Digestive and Liver Disease : Official Journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver·A CorbaniA K Burroughs
Jun 20, 2014·Alimentary Pharmacology & Therapeutics·H VidotN Shackel
Mar 28, 2018·Liver International : Official Journal of the International Association for the Study of the Liver·Motoh IwasaKazuhiko Koike
Oct 27, 2018·European Journal of Gastroenterology & Hepatology·Ai MurataHironori Tokumo
Nov 18, 2018·European Journal of Gastroenterology & Hepatology·Sherief Abd-ElsalamRehab Badawi
Jul 11, 2019·Current Gastroenterology Reports·Lena B PalmerCaitlin Homberger Green
Aug 7, 2019·Journal of Gastroenterology and Hepatology·Yasuhiko SawadaHitoshi Yoshiji
Dec 14, 2019·European Journal of Gastroenterology & Hepatology·Sherief Abd-ElsalamRehab Badawi
Mar 1, 2017·BMC Family Practice·Joannes HallegraeffCees van der Schans
May 15, 2021·Canadian Journal of Pain = Revue Canadienne De La Douleur·Franklin F GorospeCraig M Dale

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