Abstract
We studied 20 patients with typical symptoms of gastro-oesophageal reflux, to determine whether the diagnostic accuracy of 24-h pH monitoring might be retained in a test using a shorter time. The duration and number of reflux episodes were used to calculate a frequency and duration score (FDS) for the 24-h period, the daytime period, the nighttime period, a 3-h postprandial period after eating a test meal (provocation test), and a 21-h period that excluded this 3-h postprandial period. The daytime FDS was significantly higher than nighttime FDS (p less than 0.02), and there was good correlation between the 21-h FDS and the 3-h postprandial FDS (rs = 0.695; p less than 0.01). We conclude that the 3-h postprandial testing after a standard meal provocation test is a practical, accurate, and well-tolerated method of diagnosing gastro-oesophageal reflux. The results also demonstrated the relative importance of daytime as opposed to nocturnal reflux in producing symptoms and oesophagitis.
References
Oct 1, 1976·Annals of Surgery·T R DemeesterD B Skinner
Dec 1, 1969·The British Journal of Surgery·J Spencer
Jul 1, 1982·Annals of Internal Medicine·J E Richter, D O Castell
Jun 1, 1984·The British Journal of Surgery·F J BranickiJ D Hardcastle
Dec 16, 1982·The New England Journal of Medicine·W J DoddsM S Egide
Citations
Jun 1, 1992·Digestive Diseases and Sciences·R Dobhan, D O Castell
Jun 1, 1995·Digestive Diseases and Sciences·G GhillebertG Vantrappen
Jan 1, 1994·Digestive Diseases and Sciences·V A SaraswatS R Naik
Apr 1, 1996·Digestive Diseases and Sciences·R K DhimanS R Naik
Sep 21, 2000·Early Human Development·M Page, H Jeffery
Sep 21, 2006·Journal of Gastroenterology and Hepatology·Masahiko InamoriAtsushi Nakajima
Jun 1, 1990·Gut·S Kruse-AndersenT Madsen
Nov 1, 1991·Gut·S Kruse-AndersenT Madsen
Nov 21, 2013·Diseases of the Esophagus : Official Journal of the International Society for Diseases of the Esophagus·G GourcerolP Ducrotté
Mar 1, 1996·Gastroenterology Clinics of North America·J Dent, R H Holloway
Aug 1, 1988·Scandinavian Journal of Gastroenterology·G Bianchi Porro, F Pace
May 1, 1993·Scandinavian Journal of Gastroenterology·H ZhuG Bianchi Porro
Sep 1, 1993·Scandinavian Journal of Gastroenterology·J B WymanR H Holloway
Apr 1, 1988·Scandinavian Journal of Gastroenterology·F JørgensenB Hesse
Jan 31, 2002·World Journal of Gastroenterology : WJG·Hui-Ming ZhuO Sangaletti