The role of single spiking spherical neurons in a fast sensory pathway

The Journal of Experimental Biology
Javier NogueiraAngel Ariel Caputi

Abstract

One difficulty in understanding the brain is that of linking the structure of the neurons with their computational roles in neural circuits. In this paper we address this subject in a relative simple system, the fast electrosensory pathway of an electric fish, where sensory images are coded by the relative latency of a volley of single spikes. The main input to this path is a stream of discrete electric images resulting from the modulation of a self-generated carrier by the environment. At the second order cell level, a window of low responsiveness, reducing potential interference from other stimuli, follows activation of the path. In the present study, we further characterize the input-output relationship at the second order neurons by recording field potentials, and ascertain its cellular basis using in vitro whole cell patch recordings. The field potentials from freely behaving, socially interacting fish were obtained from chronically implanted fish restrained in a mesh pen. In addition, at the end of some experiments the fish was curarized and the fast electrosensory path responses to artificial stimuli were further explored. These in vivo approaches showed that larger stimuli cause larger and longer windows of low responsi...Continue Reading

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Mar 10, 2005·The Journal of Experimental Biology·Ana Carolina PereiraAngel Ariel Caputi
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Citations

Jul 27, 2011·PloS One·Javier Nogueira, Ángel Ariel Caputi
May 23, 2014·Journal of Physiology, Paris·Leticia Iribarne, María E Castelló
Aug 5, 2014·Journal of Physiology, Paris·Ana Carolina PereiraAngel A Caputi
May 22, 2007·Comparative Biochemistry and Physiology. Part A, Molecular & Integrative Physiology·María E CastellóAngel A Caputi
Jan 20, 2019·The Journal of Experimental Biology·Angel Ariel Caputi, Pedro Aníbal Aguilera
Oct 22, 2019·Frontiers in Integrative Neuroscience·Caitlin E FieldChristopher B Braun
Mar 13, 2021·The Journal of Experimental Biology·Javier NogueiraÁngel A Caputi

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