The role of sinus disease in asthma

Current Opinion in Allergy and Clinical Immunology
Claus BachertPaul Van Cauwenberge

Abstract

Some time ago, a link between upper and lower respiratory disease was described, which gave rise to the concept of 'united airways disease'. This concept primarily refers to the well established link between allergic rhinitis and asthma, but it also covers a possible link between sinus disease and asthma (allergic or nonallergic) and other lower airway disease. The current classification of chronic rhinosinusitis (CRS) includes disease without and with nasal polyps, which are considered subgroups of CRS. Different patterns of inflammatory and regulatory cytokines (involving distinguishable T-helper lymphocyte populations) and of remodelling markers, however, were recently described to differentiate nasal polyposis from CRS, yielding two discrete entities. These patterns resemble those of lower airway diseases, such as asthma and chronic obstructive pulmonary disease, and suggest a common aetiological/pathogenetic background. Whereas the link between nasal polyps and asthma is well established (indeed, asthma improves after medical or surgical treatment of sinus disease), that between CRS and lower airway disease is not well understood. Recently, Staphylococcus aureus enterotoxins, acting as superantigens, were identified as a p...Continue Reading

References

Jan 11, 1979·The New England Journal of Medicine·J M SturgessJ A Turner
Jan 1, 1977·The Journal of Allergy and Clinical Immunology·G A Settipane, F H Chafee
Jul 1, 1990·The Journal of Allergy and Clinical Immunology·P G BardinJ R Joubert
Jan 1, 1987·Acta Oto-laryngologica·H Kakoi, F Hiraide
May 1, 1968·Annals of Internal Medicine·M Samter, R F Beers
Aug 1, 1984·The Journal of Allergy and Clinical Immunology·R FriedmanP Fireman
Dec 1, 1981·International Journal of Pediatric Otorhinolaryngology·L BusincoP Bellioni
Apr 1, 1995·International Archives of Allergy and Immunology·J W GeorgitisB Stone
Mar 1, 1995·American Journal of Otolaryngology·K TakeuchiY Sakakura
Jun 1, 1994·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·G J NishiokaJ P McKinsey
Dec 1, 1993·The Journal of Allergy and Clinical Immunology·K L NguyenH L Pence
Sep 1, 1996·The Journal of Allergy and Clinical Immunology·H SuzukiT Takasaka
Sep 1, 1996·Allergy and Asthma Proceedings·K Larsen
Feb 1, 1997·Clinical Otolaryngology and Allied Sciences·N S JonesI Holland
Jun 1, 1997·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·P DemolyJ Bousquet
Jun 1, 1997·The Journal of Allergy and Clinical Immunology·C BachertC Rudack
Jul 1, 1997·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·C A OliveiraG S Rachelefsky
Jul 1, 1997·The Journal of Allergy and Clinical Immunology·G RollaC Bucca
Nov 18, 1998·Respiration; International Review of Thoracic Diseases·M OkayamaK Shirato
Jan 12, 1999·American Journal of Rhinology·C RudackC Bachert
Apr 24, 1999·The Annals of Otology, Rhinology, and Laryngology·K IkedaT Takasaka
Jul 10, 1999·The Journal of Allergy and Clinical Immunology·A Szczeklik, D D Stevenson
Jul 10, 1999·The Journal of Allergy and Clinical Immunology·C LamblinB Wallaert
Jun 14, 2000·American Journal of Respiratory and Critical Care Medicine·G J BraunstahlW J Fokkens
Nov 9, 2000·American Journal of Rhinology·C BachertP van Cauwenberge
Jan 10, 2001·The Journal of Allergy and Clinical Immunology·M BrescianiP Chanez
Mar 10, 2001·The Journal of Allergy and Clinical Immunology·G J BraunstahlW J Fokkens
Apr 11, 2001·The Journal of Allergy and Clinical Immunology·C BachertP van Cauwenberge
May 22, 2001·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·M A ToscaG W Canonica
Nov 13, 2001·American Journal of Respiratory and Critical Care Medicine·R G StirlingK F Chung
Nov 15, 2001·The Journal of Allergy and Clinical Immunology·J BousquetUNKNOWN World Health Organization
Apr 10, 2002·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·A M RiccioG Ciprandi
Apr 10, 2002·The Journal of Allergy and Clinical Immunology·Anneke ten BrinkeElisabeth H Bel
Oct 3, 2002·Current Allergy and Asthma Reports·Glenis K Scadding
Oct 3, 2002·Current Allergy and Asthma Reports·Neil Bhattacharyya
Oct 18, 2002·Clinical Otolaryngology and Allied Sciences·M M CollinsJ A Wilson
Feb 13, 2003·Current Opinion in Allergy and Clinical Immunology·Ruby Pawankar
May 14, 2003·The Journal of Allergy and Clinical Immunology·Claus BachertS G O Johansson
Jun 6, 2003·Pediatric Allergy and Immunology : Official Publication of the European Society of Pediatric Allergy and Immunology·Maria Angela ToscaGiorgio Ciprandi
Jun 27, 2003·Primary Care·Welby Winstead
Jul 16, 2003·Allergy·J BousquetP Demoly
Jul 25, 2003·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·Maria Angela ToscaGiorgio Ciprandi
Aug 19, 2003·Current Opinion in Otolaryngology & Head and Neck Surgery·Mark A Zacharek, John H Krouse
Sep 17, 2003·Archives of Otolaryngology--head & Neck Surgery·Muge OzcanUmit Tuncel

❮ Previous
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Citations

Dec 6, 2011·HNO·B A StuckUNKNOWN German Society of Otorhinolaryngology, Head and Neck Surgery
Apr 19, 2011·Current Allergy and Asthma Reports·Leandra Mfuna-EndamMartin Y Desrosiers
Mar 31, 2009·European Journal of Internal Medicine·Riccardo Polosa, Giuseppe Trifoglio Benfatto
Feb 28, 2008·Current Opinion in Pulmonary Medicine·Jung-Soo Kim, Bruce K Rubin
Nov 17, 2009·Current Opinion in Otolaryngology & Head and Neck Surgery·Mary Beth Fasano
Jul 16, 2010·International Journal of Chronic Obstructive Pulmonary Disease·Violetta M PiotrowskaAdam Antczak
Apr 30, 2009·American Journal of Rhinology & Allergy·Aaron N PearlmanRobert C Kern
Aug 26, 2014·The World Allergy Organization Journal·Anahí YáñezStephen T Holgate
Feb 12, 2014·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·Hong OuyangJingdong Du
Aug 2, 2014·Journal of Aerosol Medicine and Pulmonary Drug Delivery·Winfried MöllerSven Becker
Sep 24, 2015·Indian Journal of Otolaryngology and Head and Neck Surgery : Official Publication of the Association of Otolaryngologists of India·Jie ChengJingdong Du
Sep 30, 2010·Expert Opinion on Drug Delivery·Winfried MöllerMartin Canis
Aug 8, 2009·The Journal of Allergy and Clinical Immunology·Jean BousquetUNKNOWN Extended Global Allergy and Asthma European Network, World Allergy Organization and Allergic Rhinitis and its Impact on Asth
Jun 15, 2007·Infectious Disease Clinics of North America·Itzhak Brook
Jan 21, 2009·Periodontology 2000·Itzhak Brook
Jan 31, 2012·International Forum of Allergy & Rhinology·Andrew James WoodRichard George Douglas
Sep 3, 2010·Pediatric Pulmonology·David Gozal
Oct 6, 2012·International Forum of Allergy & Rhinology·Matthew LamRichard J Harvey
Mar 19, 2016·International Forum of Allergy & Rhinology·Clara M OlcottChristine B Franzese
Aug 29, 2006·Lancet·Stephen T Holgate, Riccardo Polosa
Dec 30, 2014·Journal of Biomedical Materials Research. Part a·J-M SeitzM Durisin
Jan 15, 2015·Respiratory Physiology & Neurobiology·A CalkovskaS Smolarova
May 12, 2016·Brazilian Journal of Otorhinolaryngology·Changzhi SunRenzhong Luo
Nov 22, 2007·Internal Medicine Journal·R Polosa
Oct 9, 2009·The Annals of Otology, Rhinology, and Laryngology·Neil Bhattacharyya, Lynn J Kepnes
Dec 1, 2012·The Annals of Otology, Rhinology, and Laryngology·Alan H ShikaniJeff G Leid
Jul 3, 2013·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·Su Jin KimSeung Youp Shin
Mar 8, 2018·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·Y LiuZ Liu
Apr 2, 2010·Allergy, Asthma & Immunology Research·An-Soo JangChoon-Sik Park
May 9, 2006·Allergy·W Fokkens, C M van Drunen
Jan 12, 2008·Current Opinion in Allergy and Clinical Immunology·Katriina KostamoTimo Sorsa
Mar 6, 2010·Expert Opinion on Pharmacotherapy·Itzhak Brook
Dec 12, 2012·Current Opinion in Allergy and Clinical Immunology·Ahmed BassiouniPeter-John Wormald
Apr 6, 2018·BioMed Research International·Giuseppe A RamirezLorenzo Dagna
May 6, 2010·Expert Review of Clinical Immunology·Enrico CompalatiGiorgio Walter Canonica
Dec 18, 2014·World Journal of Clinical Cases·En-Tong WangLi-Juan Guo

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