PMID: 11310361Apr 20, 2001Paper

The role of spiral computed tomography and D-dimer in pulmonary embolism

Scottish Medical Journal
F G Adams

Abstract

The first part of this study retrospectively compared the discriminatory power of spiral CT versus clinical findings in 112 consecutive patients referred with chest pain or dyspnoea. Spiral CT exhibited a sensitivity 91.9%; specificity 98.7%; PPV 97.1%; NPV 96.1%; accuracy 96.4%. No other test or clinical parameter had acceptable accuracy. The SimpliRED test is a latex method of estimating the level of D-dimer. The second part of this study determined that, in a similar consecutive series of patients referred for lung scintigrams, although SimpliRED tests had a NPV 95.5%, 59/126 (46.8%) consecutive were positive. However on the basis of clinical effectiveness and cost, imaging for suspected pulmonary embolism should be based on a combination of D-dimer estimation and spiral CT.

References

Sep 1, 1987·AJR. American Journal of Roentgenology·M F QuinnJ D Garnic
Nov 1, 1995·AJR. American Journal of Roentgenology·M Remy-JardinJ P Beregi

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Citations

May 26, 2006·Academic Emergency Medicine : Official Journal of the Society for Academic Emergency Medicine·Ram S DurisetiMargaret L Brandeau

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