The Role of Stressful Parenting and Mineralocorticoid Receptor Haplotypes on Social Development During Adolescence and Young Adulthood

Journal of Youth and Adolescence
H M EndedijkSusan Branje

Abstract

The development of social behavior could be affected by stressful parenting. The mineralocorticoid receptor, one of the two main receptors for the stress hormone cortisol, plays a vital role in adequate responses to stress. Therefore, the effects of stressful parenting on social development (i.e., empathic concern, perspective taking and prosocial behavior) may be moderated by functional genetic variation in mineralocorticoid receptor haplotypes (a combination of alleles). A group of 343 adolescents (44.3% females) was followed from the age of 13 until 24 years. Growth curve analyses showed lower levels of prosocial behaviors and a slower increase in empathic concern and perspective taking in adolescents who reported more stressful parenting. In contrast, relatively higher levels of prosocial behavior, empathic concern and perspective taking were present in combination with stress resilient mineralocorticoid receptor haplotypes. Despite sex differences in social development with earlier social development for girls, no consistent sex differences were found with regard to mineralocorticoid receptor haplotypes. The current study showed that genetic variation in mineralocorticoid receptor impacts the social development during adol...Continue Reading

References

Feb 1, 1995·The Journal of Endocrinology·M P CareyE R de Kloet
Jun 1, 1996·European Child & Adolescent Psychiatry·M DunizS Macari
Feb 13, 2002·Child Maltreatment·Linda Anne Valle, Jane F Silovsky
May 14, 2005·Nature Reviews. Neuroscience·E Ron de KloetFlorian Holsboer
Jan 18, 2006·American Journal of Epidemiology·Thomas A TrikalinosJohn P A Ioannidis
Feb 24, 2006·Journal of Child Psychology and Psychiatry, and Allied Disciplines·Sarah-Jayne Blakemore, Suparna Choudhury
Dec 8, 2007·Trends in Neurosciences·Marian JoëlsE Ronald de Kloet
Mar 21, 2008·Nature Reviews. Neuroscience·Sarah-Jayne Blakemore
Apr 22, 2008·European Journal of Pharmacology·Roel H DerijkFrans G Zitman
Apr 23, 2008·Current Protocols in Bioinformatics·Andreas D Baxevanis
Sep 9, 2008·Nature Genetics·Steven A McCarrollDavid Altshuler
Apr 30, 2009·Nature Reviews. Neuroscience·Sonia J LupienChristine Heim
Nov 28, 2009·Brain and Cognition·Erika E Forbes, Ronald E Dahl
Jan 1, 2005·Journal of Research on Adolescence : the Official Journal of the Society for Research on Adolescence·Nancy EisenbergStephanie A Shepard
Jul 20, 2010·Psychometrika·Albert Satorra, Peter M Bentler
Nov 9, 2010·Genetic Epidemiology·Yun LiGonçalo R Abecasis
Dec 15, 2010·Neuroscience and Biobehavioral Reviews·Marco Del GiudiceElizabeth A Shirtcliff
Mar 23, 2011·Journal of Neuroendocrinology·E F G NaninckJ Bakker
Jun 27, 2012·Journal of Personality Assessment·Skyler T HawkWim Meeus
Aug 29, 2012·Journal of Personality·Bernadette P Luengo KanacriGian Vittorio Caprara
Dec 28, 2012·Nature Methods·Olivier DelaneauJonathan Marchini
Mar 5, 2013·Journal of Child Psychology and Psychiatry, and Allied Disciplines·Bart H J BrounsWim H J Meeus
Sep 18, 2013·Developmental Psychology·Jolien Van der GraaffWim Meeus
Feb 19, 2014·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·Katja WingenfeldStefan Roepke
Dec 3, 2014·Psychoneuroendocrinology·Freija ter HeegdeChristiaan H Vinkers
Dec 17, 2014·Neurobiology of Stress·Bruce S McEwenCarla Nasca
Mar 15, 2015·Psychoneuroendocrinology·Florian HardeveldAartjan T F Beekman
Apr 22, 2015·Nature Reviews. Neuroscience·Carmen Sandi, József Haller
Jun 17, 2015·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·Bruce S McEwenJason D Gray
Aug 1, 2015·Nature Protocols·Elisabeth M van LeeuwenJouke Jan Hottenga
Aug 4, 2015·Social Development·Elinor FlynnMarion K Underwood
Sep 29, 2015·Developmental Psychology·Gustavo CarloMatthew G Nielson

❮ Previous
Next ❯

Citations


❮ Previous
Next ❯

Methods Mentioned

BETA
environmental stress
genotyping
possible

Software Mentioned

Plink
R
SHAPEIT
SNPHAP
IMPUTE
Mplus
RADAR
HardyWeinberg package
M plus

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.