The role of surgical timing in the treatment of thoracic and lumbar spinal tuberculosis

Archives of Orthopaedic and Trauma Surgery
Peng ZhangZikun Shang

Abstract

To determine the outcome and safety of surgical treatment of thoracic and lumbar spinal tuberculosis in patients without obvious clinical and laboratory improvement after preoperative short-time chemotherapy. Data of 86 patients with single-level thoracic and lumbar tuberculosis, treated by one-stage posterior instrumentation combined with anterior radical debridement and fusion, were studied retrospectively. Patients were divided into two groups based on the results of erythrocyte sedimentation rate (ESR) after preoperative 2-week chemotherapy. Surgical outcome and prognosis were compared between the two groups. After antituberculous chemotherapy for 2 weeks, the ESR did not decrease or even increase in 57 patients (group A), but decreased in 29 patients (group B). However, the ESR decreased gradually after surgery and returned to a normal level at the final follow-up in both groups. Between group A and B, no significant difference was observed in pain improvement (6.3 ± 1.4, 6.4 ± 1.4, respectively, P = 0.805). The corrected angle was 12.4° ± 5.9°, 13.8° ± 6.4°, respectively, for group A and group B (P = 0.305). It is safe and effective to carry out the surgery just after a short-time antituberculous chemotherapy. And it is t...Continue Reading

References

Jul 3, 2010·The Journal of Bone and Joint Surgery. British Volume·A K Jain
May 26, 2012·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·Oheneba Boachie-AdjeiMuharrem Yazici

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Citations

Mar 10, 2016·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·Hai-Long RenJian-Ting Chen
Jun 17, 2015·Journal of Spinal Disorders & Techniques·Barrett S BoodyAlpesh A Patel
Oct 4, 2018·Current Reviews in Musculoskeletal Medicine·Barrett S BoodyAlexander R Vaccaro
Feb 1, 2020·Current Pain and Headache Reports·Laxmaiah ManchikantiJoshua A Hirsch

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