PMID: 1213172Apr 1, 1975Paper

The role of the caudate nucleus in the development of convulsive discharges

Fiziologicheskiĭ zhurnal SSSR imeni I. M. Sechenova
R M Avakian, E B Arushanian

Abstract

A single or rhythmical (1-3/sec) stimulation of the caudate nucleus in unrestrained rats facilitated formation of slow negative waves and the spike-wave complexes in the EEG of the sensory-motor cortex and contralateral neostriatum, as well as development of behavioral disturbances due to subseisure doses of pentylentetrazol. During the low-frequency stimulation of the caudate nucleus or after its cessation, when giving the convulsant drug, regular potentials of the spike-wave type or a general seizure may occur. The caudate nucleus is supposed to be able to participate in the petit mal seizure mechanisms because of its syndhronizing influences on the cortex.

Related Concepts

Related Feeds

Basal Ganglia

Basal Ganglia are a group of subcortical nuclei in the brain associated with control of voluntary motor movements, procedural and habit learning, emotion, and cognition. Here is the latest research.

Barrel cortex

Here is the latest research on barrel cortex, a region of somatosensory and motor corticies in the brain, which are used by animals that rely on whiskers for world exploration.

Absence Epilepsy

Absence epilepsy is a common seizure disorder in children which can produce chronic psychosocial sequelae. Discover the latest research on absence epilepsies here.